Clinical trials
Schizophrenia clinical trials
Below are recruiting schizophrenia clinical trials, each written for real people, not researchers. We’re tracking 314 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06939088RecruitingPhase 2
Tirzepatide for alcohol reduction in schizophrenia
This trial tests if tirzepatide, a once-weekly injection, can help reduce heavy drinking in people who have both schizophrenia and alcohol use disorder. If you struggle with alcohol and have stable schizophrenia, this study may offer a new treatment option.
Aalborg, DenmarkAges 18–70 - NCT06278532Recruiting
Validating psychosis assessment tools in Lithuanian
This trial tests whether three psychiatric questionnaires work well for people with schizophrenia or related disorders. If you are between 18 and 65 and have one of these diagnoses, joining may help improve care for others like you.
KaunasAges 18–65 - NCT07192042Recruiting
Testing a device to check sleep breathing in schizophrenia
This trial uses a non-wearable device to assess sleep-disordered breathing in people with schizophrenia who are hospitalized. It aims to understand if this easy method can help monitor sleep issues.
New Taipei CityAges 20–70 - NCT06504290RecruitingPhase 1
Safety study of VV119 for healthy adults and people with schizophrenia
This trial tests if a new drug called VV119 is safe and how it works in the body. It is for healthy volunteers and for people who have had schizophrenia for at least a year and are currently having worsening symptoms.
Beijing, Beijing MunicipalityAges 18–65 - NCT06673966Recruiting
Schizophrenia brain and immune health study
This study looks at how immune system health relates to brain changes in people with schizophrenia. It uses brain imaging and electrical activity tests to understand these connections.
Changsha, HunanAges Any age - NCT05299749Recruiting
Brain training using real-time fMRI for hearing voices in schizophrenia
This trial tests whether real-time brain imaging “neurofeedback” can help people with schizophrenia who have ongoing auditory hallucinations (hearing voices) that haven’t improved with medications. If you qualify, you may complete brain-scanning sessions where you practice changing brain activity while being monitored.
Brockton, MassachusettsAges 18–55 - NCT05340348Recruiting
Study of a patient guide for young people at risk of psychosis
This study tests how a “patient guide” (Patientheque) may help young people who are either having a first psychosis episode or showing early warning signs. It aims to support care decisions and reduce stress by improving understanding and follow-up.
BrestAges 15–30 - NCT06456983Recruiting
Maintenance ECT for hard-to-treat schizophrenia
This trial tests if regular electroconvulsive therapy (ECT) can help people whose schizophrenia has not improved with clozapine or who cannot take clozapine. Researchers will see if maintenance ECT helps prevent symptoms from returning.
AachenAges 18–75 - NCT06588270Recruiting
Virtual reality therapy for schizophrenia symptoms
This study tests whether using virtual reality (VR) can help improve the 'negative symptoms' of schizophrenia, like low motivation or social withdrawal. You would play specially-designed VR games during therapy sessions to see if it helps you feel more engaged.
Santiago, Santiago MetropolitanAges 18–65 - NCT06595654Recruiting
rTMS for negative symptoms of schizophrenia
This trial tests if repetitive transcranial magnetic stimulation (rTMS), a non-invasive brain stimulation technique, can help reduce negative symptoms of schizophrenia like lack of motivation or social withdrawal. It might be an option if your negative symptoms are more prominent than positive ones.
Neuilly-sur-MarneAges 18 years+ - NCT06672588Recruiting
Magnetic seizure therapy for schizophrenia
This trial tests a new type of brain stimulation called magnetic seizure therapy (MST) for people with schizophrenia who haven't gotten better with standard medicines. The goal is to see if MST can help reduce symptoms like hallucinations or confusion.
Vancouver, British ColumbiaAges 18 years+ - NCT06749444Recruiting
Cognitive behavioral therapy for sleep issues in schizophrenia
This trial tests if a talking therapy focused on sleep and daily rhythms (CBT-I) can help people with schizophrenia who have not responded well to other treatments and have trouble sleeping. It aims to improve sleep quality without medication.
Glostrup, DenmarkAges 18–64 - NCT06907420Recruiting
40 Hz visual stimulation for schizophrenia
This trial tests whether a specific type of flickering light (40 Hz) can help people with schizophrenia or schizoaffective disorder. The treatment is non-invasive and may improve brain function.
Munich, BavariaAges 18 years+ - NCT07395206Recruiting
Kiso Mind App for schizophrenia or schizoaffective disorder
This study tests the Kiso Mind app, a smartphone app designed to help people with schizophrenia or schizoaffective disorder manage their symptoms. It looks at whether the app is easy to use and helpful for daily life.
Berlin, State of BerlinAges 18–65 - NCT07356765Enrolling by invitation
Berberine for negative symptoms of schizophrenia
This trial tests if berberine, a natural supplement, can help reduce negative symptoms like lack of motivation or social withdrawal in people with schizophrenia. It may work by affecting the brain and body.
TianjinAges 18–60 - NCT06229210RecruitingPhase 3
Lumateperone safety study for children with schizophrenia, bipolar, or autism
This trial tests a medication called lumateperone for children and teens with schizophrenia, bipolar disorder, or autism spectrum disorder. It aims to see if the medicine is safe and tolerable over time.
Phoenix, ArizonaAges 5–17 - NCT07424404RecruitingPhase 3
Long-term safety trial for teens with schizophrenia or autism irritability
This trial looks at the long-term safety of KarXT, a medication for schizophrenia, and KarX-EC for irritability related to autism in teenagers. It is for teens who have already completed the main part of a previous study without serious side effects.
Dothan, AlabamaAges 5–17 - NCT07680946RecruitingPhase 2
Testing ublituximab for treatment-resistant schizophrenia
This trial tests an experimental drug, ublituximab, to see if it helps people with schizophrenia that hasn't gotten better with standard treatments. It may offer a new option for those who still have significant symptoms despite current therapy.
Little Rock, ArkansasAges 18–60 - NCT02639702RecruitingPhase 4
Switching from twice-daily to once-daily clozapine for schizophrenia
This trial tests whether taking clozapine once a day (instead of twice a day) works safely for people with schizophrenia. It may help by simplifying your dosing schedule while closely monitoring your wellbeing.
Toronto, OntarioAges 18 years+ - NCT07755605Recruiting
Smartphone app training for social skills in schizophrenia
This trial tests a smartphone app designed to help people with schizophrenia or schizoaffective disorder improve their social thinking and interactions. It may be a good option if you can use an app and are on stable medication.
SeoulAges 19–60 - NCT07658898Recruiting
Brain stimulation for negative and cognitive symptoms in schizophrenia
This study tests a new type of brain stimulation called temporal interference to see if it can help with negative symptoms (like lack of motivation or emotion) and cognitive symptoms (like trouble with memory or focus) in schizophrenia. It uses a special head device to target a specific brain area.
ShanghaiAges 18–65 - NCT07459647RecruitingPhase 2
Long-term study of ML-007C-MA for schizophrenia
This trial tests a new drug, ML-007C-MA, for adults with schizophrenia who may benefit from ongoing treatment. It aims to see how safe and effective the drug is over a longer period.
Little Rock, ArkansasAges 18–65 - NCT07177261Recruiting
Brain synchrony study for schizophrenia
This study looks at how brain activity syncs between people with schizophrenia and others. It aims to understand social interaction differences—potentially leading to better treatments.
Los Angeles, CaliforniaAges 18–65 - NCT05102929Recruiting
Brain-training for working memory in early schizophrenia
This study looks at whether a treatment that targets brain “rhythms” can improve working memory in people who are in the early stage of schizophrenia. It may help the brain process information more effectively, which can support daily thinking and functioning.
Pittsburgh, PennsylvaniaAges 18–40
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Schizophrenia trials by city
Studies with a site in or near these metro areas.
Schizophrenia trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for schizophrenia?
- Yes. Clin2 currently lists 314 recruiting schizophrenia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a schizophrenia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a schizophrenia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.