Clinical trials
Schizophrenia clinical trials
Below are recruiting schizophrenia clinical trials, each written for real people, not researchers. We’re tracking 307 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06939088RecruitingPhase 2
Tirzepatide for alcohol reduction in schizophrenia
This trial tests if tirzepatide, a once-weekly injection, can help reduce heavy drinking in people who have both schizophrenia and alcohol use disorder. If you struggle with alcohol and have stable schizophrenia, this study may offer a new treatment option.
Aalborg, DenmarkAges 18–70 - NCT06278532Recruiting
Validating psychosis assessment tools in Lithuanian
This trial tests whether three psychiatric questionnaires work well for people with schizophrenia or related disorders. If you are between 18 and 65 and have one of these diagnoses, joining may help improve care for others like you.
KaunasAges 18–65 - NCT07759895RecruitingPhase 2
Two-drug treatment for negative symptoms of schizophrenia
This trial tests two medicines, deferiprone and N-acetylcysteine, taken together to see if they improve negative symptoms of schizophrenia, such as lack of motivation or pleasure. It aims to find a new option for people who still have these symptoms despite their current antipsychotic treatment.
JerusalemAges 18–40 - NCT06595654Recruiting
rTMS for negative symptoms of schizophrenia
This trial tests if repetitive transcranial magnetic stimulation (rTMS), a non-invasive brain stimulation technique, can help reduce negative symptoms of schizophrenia like lack of motivation or social withdrawal. It might be an option if your negative symptoms are more prominent than positive ones.
Neuilly-sur-MarneAges 18 years+ - NCT07395206Recruiting
Kiso Mind App for schizophrenia or schizoaffective disorder
This study tests the Kiso Mind app, a smartphone app designed to help people with schizophrenia or schizoaffective disorder manage their symptoms. It looks at whether the app is easy to use and helpful for daily life.
Berlin, State of BerlinAges 18–65 - NCT07356765Enrolling by invitation
Berberine for negative symptoms of schizophrenia
This trial tests if berberine, a natural supplement, can help reduce negative symptoms like lack of motivation or social withdrawal in people with schizophrenia. It may work by affecting the brain and body.
TianjinAges 18–60 - NCT06907420Recruiting
40 Hz visual stimulation for schizophrenia
This trial tests whether a specific type of flickering light (40 Hz) can help people with schizophrenia or schizoaffective disorder. The treatment is non-invasive and may improve brain function.
Munich, BavariaAges 18 years+ - NCT07192042Recruiting
Testing a device to check sleep breathing in schizophrenia
This trial uses a non-wearable device to assess sleep-disordered breathing in people with schizophrenia who are hospitalized. It aims to understand if this easy method can help monitor sleep issues.
New Taipei CityAges 20–70 - NCT06749444Recruiting
Cognitive behavioral therapy for sleep issues in schizophrenia
This trial tests if a talking therapy focused on sleep and daily rhythms (CBT-I) can help people with schizophrenia who have not responded well to other treatments and have trouble sleeping. It aims to improve sleep quality without medication.
Glostrup, DenmarkAges 18–64 - NCT06672588Recruiting
Magnetic seizure therapy for schizophrenia
This trial tests a new type of brain stimulation called magnetic seizure therapy (MST) for people with schizophrenia who haven't gotten better with standard medicines. The goal is to see if MST can help reduce symptoms like hallucinations or confusion.
Vancouver, British ColumbiaAges 18 years+ - NCT06673966Recruiting
Schizophrenia brain and immune health study
This study looks at how immune system health relates to brain changes in people with schizophrenia. It uses brain imaging and electrical activity tests to understand these connections.
Changsha, HunanAges Any age - NCT06504290RecruitingPhase 1
Safety study of VV119 for healthy adults and people with schizophrenia
This trial tests if a new drug called VV119 is safe and how it works in the body. It is for healthy volunteers and for people who have had schizophrenia for at least a year and are currently having worsening symptoms.
Beijing, Beijing MunicipalityAges 18–65 - NCT06456983Recruiting
Maintenance ECT for hard-to-treat schizophrenia
This trial tests if regular electroconvulsive therapy (ECT) can help people whose schizophrenia has not improved with clozapine or who cannot take clozapine. Researchers will see if maintenance ECT helps prevent symptoms from returning.
AachenAges 18–75 - NCT05299749Recruiting
Brain training using real-time fMRI for hearing voices in schizophrenia
This trial tests whether real-time brain imaging “neurofeedback” can help people with schizophrenia who have ongoing auditory hallucinations (hearing voices) that haven’t improved with medications. If you qualify, you may complete brain-scanning sessions where you practice changing brain activity while being monitored.
Brockton, MassachusettsAges 18–55 - NCT05340348Recruiting
Study of a patient guide for young people at risk of psychosis
This study tests how a “patient guide” (Patientheque) may help young people who are either having a first psychosis episode or showing early warning signs. It aims to support care decisions and reduce stress by improving understanding and follow-up.
BrestAges 15–30 - NCT07459647RecruitingPhase 2
Long-term study of ML-007C-MA for schizophrenia
This trial tests a new drug, ML-007C-MA, for adults with schizophrenia who may benefit from ongoing treatment. It aims to see how safe and effective the drug is over a longer period.
Little Rock, ArkansasAges 18–65 - NCT03495024RecruitingPhase 4
Varenicline for quitting smoking in people with schizophrenia
This trial tests whether varenicline helps people with schizophrenia or schizoaffective disorder stop smoking. It also looks at related nervous-system side effects that can happen with some anti-psychotic medicines.
Philadelphia, PennsylvaniaAges 18–75 - NCT02640911Recruiting
Long-term study of certain antipsychines in schizophrenia
This is an observational (non-intervention) study that follows adults with schizophrenia who are taking specific “atypical” antipsychotic medicines long-term. Researchers want to learn about patients’ experiences and outcomes while on these treatments.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT03094429RecruitingPhase 2/Phase 3
Testing NaBen add-on to clozapine for tough schizophrenia symptoms
This trial tests whether adding NaBen (a supplement-like medicine) to clozapine can improve “residual” symptoms in adults with difficult-to-treat schizophrenia. The study also checks safety and the best dose, using a placebo (inactive pill) for comparison.
Pasadena, CaliforniaAges 18–55 - NCT05074732Recruiting
Study of forensic mental health admissions after a service move
This study looks at all adult admissions to Ireland’s National Forensic Mental Health Service during a specific time window. It may help improve how the new forensic service at Portrane runs in the future.
DublinAges 18 years+ - NCT01392885Recruiting
Brain health and exercise program for schizophrenia
This trial studies how a structured exercise program may affect brain health in people with schizophrenia or schizoaffective disorder. It may help researchers understand whether exercise can support brain function and overall health in this condition.
Vancouver, British ColumbiaAges 19–45 - NCT07856381Recruiting
Studying social skills and brain changes in schizophrenia
This study looks at how social thinking and brain structure change over time in people with schizophrenia compared to healthy adults. It uses brain scans to see if iron levels in the brain play a role.
Innsbruck, TyrolAges 18–70 - NCT07858565Recruiting
Quality of life with quetiapine for schizophrenia or bipolar disorder
This study looks at how well patients feel and how safe it is when taking quetiapine alone or with other medicines for schizophrenia or bipolar disorder. It aims to help doctors understand the best ways to use this treatment.
SarajevoAges 18–65 - NCT06431009Recruiting
Danish schizophrenia study for recent first episodes
This study follows people who have recently been diagnosed with a first episode of schizophrenia, schizoaffective disorder, or are at ultra-high risk for psychosis. Researchers want to learn more about how these conditions develop over time to improve early care and treatment.
AarhusAges 15 years+
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Schizophrenia trials by city
Studies with a site in or near these metro areas.
Schizophrenia trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for schizophrenia?
- Yes. Clin2 currently lists 307 recruiting schizophrenia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a schizophrenia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a schizophrenia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.