Clinical trials
Sexually Transmitted Diseases clinical trials
Below are recruiting sexually transmitted diseases clinical trials, each written for real people, not researchers. We’re tracking 19 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06525064Recruiting
Health-E You app study for teen guys
This study tests a health app designed for teen guys who have had vaginal or anal sex. It aims to see if the app can help with sexual health decisions and education.
Oakland, CaliforniaAges 13–21 - NCT05910580Recruiting
Screening and support for alcohol and substance risk in adults
This study aims to improve care access and outcomes for adults who screen positive for risky alcohol or drug use. If you qualify, you may be offered ways to connect to support during your reproductive years.
Boston, MassachusettsAges 18 years+ - NCT06007534Recruiting
Doxycycline for STI Prevention After Sex
This study looks at how a single 200 mg dose of doxycycline works in the body to prevent bacterial sexually transmitted infections (like chlamydia, gonorrhea, and syphilis) after a risky sexual encounter. It is for men who have sex with men and are already on PrEP or living with HIV.
ParisAges 18–100 - NCT06579781Recruiting
Parent toolkit study for Georgia families with teens
This study tests a parent toolkit to support families with 12- to 15-year-olds. Families living together in certain Georgia areas may join to help improve communication and health.
Cairo, GeorgiaAges 12–15 - NCT07500415Recruiting
Doxycycline to prevent STIs in Rio de Janeiro
This trial tests whether taking the antibiotic doxycycline can prevent sexually transmitted infections (STIs) like chlamydia, gonorrhea, and syphilis in people at higher risk. If you are a man or transgender woman who has sex with men, are living with HIV or on PrEP, and have had an STI in the past year, you may be able to join.
Rio de Janeiro, Rio de JaneiroAges 18 years+ - NCT07199998Recruiting
How tampons and cups affect your vaginal health
This study looks at how tampons and menstrual cups affect your body's natural defenses and the healthy bacteria in your vagina. You might join if you are a healthy woman between 18 and 49 who has regular periods and uses or is willing to use these products.
Paris, Île-de-France RegionAges 18–49 - NCT05463692Enrolling by invitation
Study of STI prevention and sexual health in Alabama women
This study follows women in Alabama to better understand sexual health and STI prevention over time. You may be able to join if you recently had an STI report and you’re currently negative for HIV, gonorrhea, and syphilis.
Birmingham, AlabamaAges 18–89 - NCT04372485Recruiting
Text-message support to help teens finish STI antibiotics
This trial tests whether a mobile phone text-message program can help teens stick to their outpatient antibiotic treatment for common sexually transmitted infections (STIs). It may help improve cure rates by supporting correct medication timing and completion.
Washington D.C., District of ColumbiaAges 15–21 - NCT04372875Recruiting
Help for teens using health tech in the emergency room
This trial tests whether using a health information technology tool in the emergency department can improve sexual health care and reduce health disparities for teens. It focuses on gathering survey and screening information so care can better meet needs.
Washington D.C., District of ColumbiaAges 15–21 - NCT04762134Recruiting
Doxycycline to prevent future bacterial STIs in high-risk men
This trial tests whether taking doxycycline can lower the chance of getting bacterial sexually transmitted infections like syphilis, gonorrhea, and chlamydia. It is aimed at men who have had these infections recently and expect to keep having multiple male partners.
Calgary, AlbertaAges 18 years+ - NCT04855773Recruiting
Mobile text-message support to help people stay on PrEP
This trial tests whether phone-based (iPhone/Android) text-message support can improve how consistently people use PrEP, an HIV prevention medicine. It may help you stay on track with refills and clinic visits, especially if you’re at higher risk of stopping PrEP.
San Francisco, CaliforniaAges 15 years+ - NCT05326061Recruiting
Study for people at high risk of getting HIV
This registry study looks at people who are HIV-negative but at high risk of getting HIV, to better understand risk and care needs. If you qualify, you may be asked to share health and behavior information to help guide future prevention efforts.
ViennaAges 18–100 - NCT05516069Recruiting
Using a self-serve kiosk to test for HIV and reduce harm
This study tests an interactive, self-serve machine (kiosk) to help people access HIV testing and other harm-reduction services more easily. It may help by making testing and support more private and simpler to use.
Moncton, New BrunswickAges 16 years+ - NCT06414408RecruitingEarly Phase 1
Doxy-PEP study for STI prevention
This trial studies whether giving the antibiotic doxycycline right after sex (known as Doxy-PEP) can prevent STIs. It asks participants to provide hair, blood, and urine samples and follow specific guidelines about hair and condom use.
San Francisco, CaliforniaAges 18 years+ - NCT06951438Recruiting
STI self-swab testing with telemed abortion
This study offers patients having a medication abortion through telemedicine the option to do their own self-swabs for STI testing at home, to see if people find this approach acceptable and easy.
Honolulu, HawaiiAges 14 years+ - NCT06574321Enrolling by invitation
Wrap It Up: A school program for healthy relationships
This study tests a school-based program called 'Wrap It Up' that teaches teens about healthy relationships and safer sex. The program is done in groups over two years, and the study compares doing it first versus later.
Scotts Valley, CaliforniaAges 16–19 - NCT06127277Enrolling by invitation
Mobile relationship program for youth in foster care
This study tests a fully mobile program designed to help youth in foster care build healthy relationships. If you join, you'll use an app on your device to learn skills and connect with others.
Berkeley, CaliforniaAges 16–19 - NCT06082453Recruiting
Modernizing syphilis testing in pregnancy and beyond
This study is testing a new, faster way to check for syphilis in pregnant people, new mothers, and their newborns, as well as in men and non-pregnant people at a Harris Health clinic. The goal is to make sure more people get the right treatment quickly.
Los Angeles, CaliforniaAges Up to 45 years - NCT07215325RecruitingPhase 4
Can doxycycline prevent STIs in men?
This trial tests if taking doxycycline after sex can lower the risk of getting sexually transmitted infections (STIs) in men who have sex with men and are at higher risk.
Atlanta, GeorgiaAges 18 years+
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Sexually Transmitted Diseases trials by city
Studies with a site in or near these metro areas.
Sexually Transmitted Diseases trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for sexually transmitted diseases?
- Yes. Clin2 currently lists 19 recruiting sexually transmitted diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a sexually transmitted diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a sexually transmitted diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.