Clinical trials
Sexually Transmitted Infection clinical trials
Below are recruiting sexually transmitted infection clinical trials, each written for real people, not researchers. We’re tracking 30 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07500415Recruiting
Doxycycline to prevent STIs in Rio de Janeiro
This trial tests whether taking the antibiotic doxycycline can prevent sexually transmitted infections (STIs) like chlamydia, gonorrhea, and syphilis in people at higher risk. If you are a man or transgender woman who has sex with men, are living with HIV or on PrEP, and have had an STI in the past year, you may be able to join.
Rio de Janeiro, Rio de JaneiroAges 18 years+ - NCT06860945Recruiting
Predicting STIs in people on HIV PrEP in Spain
This study is for people in Spain who are starting or already taking PrEP pills to prevent HIV. It aims to create a tool that can help predict who might get a sexually transmitted infection while on PrEP, so doctors can offer better monitoring or prevention.
AlmeríaAges 16 years+ - NCT07290439Recruiting
Fast STI testing for pregnant women
This study tests a quick way to check for STIs during pregnancy or labor at Grady Memorial Hospital. It aims to improve health for mothers and babies by finding infections early.
Atlanta, GeorgiaAges Any age - NCT06793605Recruiting
Community study of MG infection in men who have sex with men
This study is about understanding how common Mycoplasma genitalium (a bacteria that can cause infection) is in men who have sex with men in Hong Kong. If you join, it will help doctors learn more about this infection in your community.
Hong KongAges 18 years+ - NCT07089836Recruiting
Syphilis blood test study for at-risk and healthy people
This study tests two new blood tests for syphilis. It compares them to approved tests using blood from people who may have or had syphilis, including pregnant women, HIV-positive people, and healthy volunteers.
Lancaster, CaliforniaAges 13 years+ - NCT06738407RecruitingPhase 4
Doxycycline to prevent STIs in high-risk people
This study tests whether taking a daily antibiotic (doxycycline) can prevent sexually transmitted infections in people at high risk. If you've had an STI recently and sometimes have sex without condoms, you might be able to join.
Los Angeles, CaliforniaAges 13–29 - NCT06266416Recruiting
Black caregivers & girls empowerment study
This study tests a program called IMARA to support black male caregivers and the girls they care for. It aims to improve family relationships and reduce risky behaviors in girls.
Chicago, IllinoisAges 13 years+ - NCT05492565Enrolling by invitation
Follow-up study for people on HIV prevention pills
This study follows adults who are at high risk of getting HIV while they take HIV prevention pills (PrEP). It aims to learn how well PrEP fits real-life use in people at risk and who may need extra care.
Seville, AndalusiaAges 18 years+ - NCT05244967Recruiting
Study of sexually transmitted infections and female fertility impact
This study looks at how sexually transmitted infections affect female fertility. It mainly enrolls young adults to better understand patterns and outcomes over time.
LübeckAges 18–22 - NCT06953310Recruiting
Farming program for teen girls' health and well-being
This study tests whether a farming program that provides food and support can help improve the health and well-being of teenage girls and young women. It is for girls aged 15-19 who are in school, not pregnant, and whose families struggle with food shortages.
KisumuAges 15 years+ - NCT07509853Recruiting
Pleasure-Focused Harm Reduction for Chemsex and Substance Use
This study explores how adding conversation about sexual pleasure to harm reduction services can help men who have sex with men and transgender persons who use drugs during sex or use other substances. If you join, you may learn new ways to reduce risks while still enjoying your sex life.
Pathum Wan, BangkokAges 18 years+ - NCT07846241Recruiting
Sexual behavior and risk of infections in young adults
This study looks at how young adults' sexual behavior and risk perception relate to getting sexually transmitted infections (STIs). By participating, you'll help researchers better understand how to prevent STIs in people your age.
BarcelonaAges 18–25 - NCT04855773Recruiting
Mobile text-message support to help people stay on PrEP
This trial tests whether phone-based (iPhone/Android) text-message support can improve how consistently people use PrEP, an HIV prevention medicine. It may help you stay on track with refills and clinic visits, especially if you’re at higher risk of stopping PrEP.
San Francisco, CaliforniaAges 15 years+ - NCT07755618Enrolling by invitationPhase 1
Doxycycline levels and adherence study
This study looks at how the antibiotic doxycycline stays in your body and how well people stick to taking it. It may help find better ways to prevent infections.
Chapel Hill, North CarolinaAges 18–65 - NCT07512856Recruiting
Support Service for Transgender People Using Substances
This study tests a new support program designed specifically for transgender people who use drugs or engage in chemsex (using drugs during sexual activity). The program aims to reduce health risks and provide safer, more culturally respectful care.
Pathum Wan, BangkokAges 18 years+ - NCT07512869Recruiting
Harm Reduction Support for Men Who Have Sex With Men in Bangkok
This study explores ways to support men who have sex with men (MSM) in Bangkok who use drugs during sexual activities, called 'chemsex.' Researchers want to understand how community leaders, healthcare workers, and police can work together to keep people safer and healthier.
Pathum Wan, BangkokAges 18 years+ - NCT07505875Recruiting
Study to create transgender-friendly services for chemsex support
This study aims to develop healthcare services tailored to transgender people regarding chemsex (using drugs during sex). Researchers will interview participants to understand their needs and experiences.
Pathum Wan, BangkokAges 18 years+ - NCT07433985Recruiting
California mobile app study for men after jail release
This study tests a mobile app to help men recently released from jail or prison who use drugs or have sex with men stay healthy and avoid HIV. It's for people who don't have HIV and live in certain California counties.
Oakland, CaliforniaAges 18–59 - NCT06778083Recruiting
Antibiotic to prevent STIs and its effect on resistance
This study looks at taking doxycycline to prevent sexually transmitted infections (STIs) in men who have sex with men. It focuses on how this approach might affect the body's resistance to antibiotics.
LondonAges 18 years+ - NCT07215325RecruitingPhase 4
Can doxycycline prevent STIs in men?
This trial tests if taking doxycycline after sex can lower the risk of getting sexually transmitted infections (STIs) in men who have sex with men and are at higher risk.
Atlanta, GeorgiaAges 18 years+ - NCT06919614RecruitingPhase 3
Testing STIs to Improve PrEP Use in Pregnancy
This trial tests whether STI testing during pregnancy helps more women start and stay on PrEP (a daily pill that prevents HIV). If you join, you'll help find better ways to protect both mother and baby from HIV.
GaboroneAges Any age - NCT06203951Recruiting
Better STI testing during pregnancy in Kenya
This study tests a simpler way to check for sexually transmitted infections (STIs) and HIV/syphilis during pregnancy in Kenyan clinics, to help keep both you and your baby healthy.
Homa BayAges Any age - NCT06743204Recruiting
Testing for sexually transmitted infections in women at risk for HIV
This study tests if combining sexually transmitted infection (STI) testing with HIV prevention medication (PrEP) helps control the HIV epidemic. It is for sexually active women aged 15-39 who live in Rakai and recently participated in a community health survey.
KalisizoAges 15–39 - NCT06082453Recruiting
Modernizing syphilis testing in pregnancy and beyond
This study is testing a new, faster way to check for syphilis in pregnant people, new mothers, and their newborns, as well as in men and non-pregnant people at a Harris Health clinic. The goal is to make sure more people get the right treatment quickly.
Los Angeles, CaliforniaAges Up to 45 years
Hear when a new Sexually Transmitted Infection trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for sexually transmitted infection?
- Yes. Clin2 currently lists 30 recruiting sexually transmitted infection studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a sexually transmitted infection trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a sexually transmitted infection trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.