Clinical trials
Surgical Site Infection clinical trials
Below are recruiting surgical site infection clinical trials, each written for real people, not researchers. We’re tracking 70 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07395518Enrolling by invitation
Drain placement in c-section for women with thick belly fat
This trial tests if placing a small drain under the skin during a cesarean section reduces surgical site infections in women with a belly fat thickness of 4 cm or more. It may help prevent infections and improve recovery.
Chon Buri, Changwat Chon BuriAges 18 years+ - NCT06439953Recruiting
Irrigation solution for spinal surgery instrumentation
This trial tests a solution used to clean the surgical site during spine surgeries to see if it helps prevent infections. It is for patients having certain types of spine surgery for conditions like deformity, cancer, or trauma.
Providence, Rhode IslandAges 18 years+ - NCT05586776RecruitingPhase 4
Using skin cleaning to prevent post-surgery wound infections
This trial tests a “skin decolonization” routine using medicated skin cleaning to help lower the risk of surgical site infections after abdominal surgery. You may be eligible if you recently had an open abdominal incision and your wound is healing as expected at discharge.
Newport Beach, CaliforniaAges 18 years+ - NCT03561376RecruitingEarly Phase 1
Zinc ointment versus petroleum jelly after skin surgery
This early-phase trial compares zinc oxide ointment versus petroleum jelly to help healing and scar appearance after certain skin surgeries. You might be able to join if you are having a suitable, uninfected, non-scalp skin incision and can use the study ointment.
Pittsburgh, PA, PennsylvaniaAges 18 years+ - NCT04256798RecruitingPhase 3
Respiratory care after high-risk abdominal surgery
This trial looks at a breathing-focused care plan given around the time of major abdominal surgery to improve recovery and outcomes. You may be eligible if you’re having a large midline abdominal incision and can be followed after surgery.
Botucatu, São PauloAges 10–100 - NCT04725916Recruiting
Study of water exposure and drain-related risks after certain surgeries
This trial looks at how using water (like showers) affects risks related to surgical drains after specific cosmetic or reconstructive procedures. Your results may help improve post-surgery safety guidance for patients who go home with drains.
Danville, PennsylvaniaAges 18 years+ - NCT05502380RecruitingPhase 3
Antibiotic prevention study for high-risk bone and spine surgeries
This Phase 3 study tests whether giving a broad set of preventive antibiotics before certain high-risk orthopedic surgeries lowers the chance of serious wound or bone infection. It mainly targets people who have contaminated wounds, tumor-related surgery, or known high-risk germs on the skin.
ZurichAges 18 years+ - NCT05852158RecruitingPhase 4
Antibiotics to prevent infection after jaw surgery
This trial tests whether giving antibiotics can lower the chance of infection after orthognathic (jaw) surgery. It may help by preventing post-surgery infections, but participation depends on your health history and medication allergies.
Halifax, Nova ScotiaAges 16 years+ - NCT05959603RecruitingPhase 3
Vancomycin powder during spinal surgery to prevent infection
This Phase 3 trial tests whether placing vancomycin powder in the wound during spinal fusion surgery can lower the chance of a surgical site infection. You might qualify if you’re having a specific type of spinal surgery and meet safety criteria.
Petah TikvaAges 18–90 - NCT05989386RecruitingPhase 2/Phase 3
Washing the belly to prevent infections after emergency surgery
This trial compares two solutions (salt water vs. povidone-iodine antiseptic) used to clean the belly during emergency surgery. The goal is to see which one better prevents wound infections.
Karachi, SindhAges 18–60 - NCT06302335RecruitingPhase 3
Iodine rinse vs salt water rinse in planned colon surgery
This study compares using povidone-iodine (an iodine-based cleaner) versus saline (salt water) to rinse the surgical area during planned colon or rectal surgery. The goal is to see which helps prevent infections at the surgery site after the operation.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT06309368RecruitingPhase 4
Wound irrigation method for ileostomy closure
This trial tests whether irrigating (cleaning) the wound with a special solution before closing the ostomy site helps it heal better, compared to the usual method. If you're having a loop ileostomy reversal, you may qualify.
Las Vegas, NevadaAges 18 years+ - NCT06363877RecruitingPhase 3
Testing a germ-killing rinse during abdominal surgery
This trial is testing whether a diluted povidone-iodine (a common germ-killer) rinse inside the belly during surgery can prevent infections better than a plain saltwater rinse. It is for adults having abdominal surgery for certain types of wounds.
Loma Linda, CaliforniaAges 18–80 - NCT06378359Recruiting
Preventing staph infections with pre-surgery decolonization
This trial tests if a simple at-home treatment (using a nasal ointment and special body wash) before surgery can prevent staph infections at the surgical site. It's for adults having outpatient surgery in several specialties, like orthopedics or general surgery.
Minneapolis, MinnesotaAges 18 years+ - NCT06586749Recruiting
Nurse-led education and phone support to reduce infections after heart bypass
This study tests whether a special nurse-led program of phone calls and education can help reduce infections after heart bypass surgery. You may be eligible if you are at higher risk for infection and have a smartphone.
Heraklion, CreteAges 18 years+ - NCT06603961Recruiting
Preventing leg swelling after bypass surgery with a special bandage
This trial tests a custom pressure-guided elastic bandage to prevent leg swelling after coronary artery bypass surgery. The bandage is wrapped around the leg where a vein was taken for the bypass.
Bangkok, Bangkok NoiAges 18 years+ - NCT06626399Recruiting
ChatGPT-4 for detecting surgical site infections after colorectal surgery
This trial tests whether ChatGPT-4 can help detect surgical site infections after colorectal surgery by looking at your electronic health records. It aims to improve infection monitoring without extra tests or visits.
Granollers, BarcelonaAges 18 years+ - NCT06638567Recruiting
Comparing insulin methods after surgery for type 2 diabetes
This trial tests two ways to give insulin after gastrointestinal or vascular surgery to see which one leads to fewer wound infections. It may help if you have type 2 diabetes and are having one of these surgeries.
AmsterdamAges 18 years+ - NCT06649890Recruiting
Testing a new irrigation solution in breast reconstruction after mastectomy
This study tests a new surgical irrigation solution (Xperience) used during breast reconstruction after double mastectomy. It aims to see if it can reduce complications and improve outcomes for people receiving implants or tissue expanders.
Chapel Hill, North CarolinaAges 18 years+ - NCT07275307Recruiting
Test of a wound gel to prevent infections after heart surgery
This study tests whether a special gel applied to the chest incision during heart surgery can lower the chance of wound infections. The gel may help keep the incision site clean and help it heal better.
San Donato Milanese, MichiganAges 18 years+ - NCT07003906Recruiting
Negative pressure therapy for emergency belly surgery incisions
This trial tests if negative pressure wound therapy (a special dressing that uses gentle suction) helps heal large cuts from emergency belly surgery better than a standard dressing. It may reduce infections and improve recovery.
EskilstunaAges 18 years+ - NCT07125196Recruiting
Infection after surgery and depression risk
This study looks at whether people who get an infection after orthopedic surgery are more likely to become depressed. If you had a surgical site infection after a limb or spine surgery, the researchers will check in on your mood over time.
BordeauxAges 18 years+ - NCT07130656Recruiting
AI for detecting deep infections after planned colorectal surgery
This trial is testing an AI system to help catch deep infections after planned colorectal surgery. If you had a planned operation on your colon or rectum without a stoma or an active infection at that time, you may be eligible.
Granollers, BarcelonaAges 18 years+ - NCT07311395Recruiting
Gentamicin injection to prevent infection after planned C-section
This study tests whether a local injection of gentamicin, an antibiotic, into the incision area can help prevent infections after a planned C-section. It may offer extra protection beyond standard antibiotics.
NahariyaAges 18 years+
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Surgical Site Infection trials by city
Studies with a site in or near these metro areas.
Surgical Site Infection trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for surgical site infection?
- Yes. Clin2 currently lists 70 recruiting surgical site infection studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a surgical site infection trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a surgical site infection trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.