Clinical trials
Sjögren's Syndrome clinical trials
Below are recruiting sjögren's syndrome clinical trials, each written for real people, not researchers. We’re tracking 29 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04848870Recruiting
Check dental and gum health in Sjögren’s disease
This study looks at dental and gum (periodontal) health in adults with Sjögren’s syndrome. It may help researchers understand how Sjögren’s affects the mouth and how patients can be supported better.
Ivry-sur-Seine, Île-de-France RegionAges 18 years+ - NCT06780293RecruitingPhase 2
Laser acupuncture for dry eye and Sjogren's dry eye
This study tests if laser acupuncture can help people with dry eye symptoms, including those with Sjogren's syndrome, which causes dryness in the eyes and mouth. It may be a good fit if you have dry eye or Sjogren's and meet the age and eye test requirements.
Taipei, TaiwanAges 20–75 - NCT04981145RecruitingPhase 4
Iguratimod for Sjögren’s syndrome symptoms and safety
This trial studies whether iguratimod improves symptoms in people with primary Sjögren’s syndrome, and checks how safe it is. It focuses on people with confirmed disease markers (anti-SSA/Ro-60) and ongoing dry eyes and dry mouth.
Hangzhou, ZhejiangAges 18–70 - NCT05113004RecruitingPhase 2
Testing new outcomes in primary Sjögren’s syndrome
This Phase 2 study tests how to measure changes in primary Sjögren’s syndrome symptoms and body activity. It may help researchers confirm which outcomes best reflect improvement and how different patient types respond to treatment.
BrestAges 18 years+ - NCT06747949RecruitingPhase 3
Long term extension study of dazodalibep for Sjogren's syndrome
This study gives continued access to the study drug dazodalibep for people with Sjogren's syndrome who completed a prior phase 3 study. The goal is to see how safe and effective the medication is over a longer period.
Avondale, ArizonaAges 18 years+ - NCT03681964Recruiting
Check tests for suspected Sjögren’s syndrome
This study follows people who have signs that might mean Sjögren’s syndrome and looks at how well a standardized work-up identifies the condition. It may help doctors confirm the diagnosis earlier and more consistently.
BrestAges 18 years+ - NCT03003572Recruiting
Test an immune marker in primary Sjögren’s disease activity
This study looks at an immune reaction (called anti-Ro/SSA IgE) to see how active primary Sjögren’s disease is. It may help doctors better understand what’s driving symptoms and activity levels over time.
BourgoinAges 18 years+ - NCT07324733Recruiting
PSMA PET scan for Sjögren's syndrome
This study uses a special PET scan called PSMA to look at inflammation in Sjögren's syndrome, comparing the results with another type of PET scan (FAPI). It may help doctors better understand the disease and find new ways to track it.
BeijingAges 18–80 - NCT04931160Recruiting
Study for suspected Sjögren’s disease diagnosis
This study follows people who may have Sjögren’s disease to better understand how to diagnose it. If you have symptoms like dry eyes or dry mouth, this could help researchers confirm the diagnosis and learn what tests best explain it.
BrestAges 18 years+ - NCT07277257RecruitingPhase 4
New dry eye treatment for people with Sjögren's syndrome
This study tests a new treatment for dry eye disease caused by Sjögren's syndrome. It may help people who still have dry eye symptoms even when using artificial tears.
Venice, FloridaAges 18 years+ - NCT06440525RecruitingPhase 2
Testing RSLV-132 for Sjögren's disease in women
This study tests an investigational drug called RSLV-132 in women with Sjögren's disease to see if it can reduce symptoms like fatigue and dryness. You may join if you've been diagnosed in the last 30 years and have persistent symptoms.
Chula Vista, CaliforniaAges 18–75 - NCT06338735Recruiting
High-frequency ultrasound for Sjögren's diagnosis
This study uses a special, very high-frequency ultrasound to take detailed images of the small glands that can be affected in Sjögren's syndrome. The goal is to see if this new ultrasound technique can help doctors diagnose Sjögren's more accurately.
PisaAges 18 years+ - NCT06401811Recruiting
Turkish swallowing questionnaire study for Sjögren's syndrome
This study tests a Turkish version of a swallowing questionnaire (EAT-10) to see if it is reliable and accurate for people with primary Sjögren's syndrome. Taking part could help doctors better understand and track swallowing problems in this condition.
AnkaraAges 18 years+ - NCT06528197Recruiting
Building a better treatment model for Sjögren's syndrome
This study is building a new model to help doctors treat primary Sjögren's syndrome using a combination of traditional Chinese medicine and Western medicine. It may help find better ways to manage your symptoms.
Beijing, Beijing MunicipalityAges 18–75 - NCT06875102Recruiting
Treating fatigue in Sjögren's syndrome with auricular stimulation
This trial tests three non-medication strategies for fatigue in Sjögren's syndrome, including a type of ear stimulation. It aims to find a better way to help people who have had fatigue for at least 6 months with no clear cause.
Saint-EtienneAges 18 years+ - NCT07118241RecruitingPhase 2
Testing a new eye drop for Sjögren's dry eye
This trial tests a new eye drop made from a natural protein (rhPRG4) to see if it safely and effectively relieves dry eye symptoms in people with Sjögren's syndrome. You'll be randomly assigned to receive the study drop or a placebo (inactive) drop for several weeks.
Sydney, New South WalesAges 18–80 - NCT06519617Enrolling by invitationPhase 2
Combined Chinese and Western medicine for Sjögren's gland damage
This trial tests whether adding traditional Chinese medicine to standard care can help repair gland damage caused by Sjögren's syndrome. It is for people with primary Sjögren's who have a specific traditional Chinese medicine pattern called 'qi and yin deficiency'.
Beijing, Beijing MunicipalityAges 18–75 - NCT03509064Recruiting
Study of quality of life in Sjögren nerve pain
This trial looks at people with Sjögren who may have small-fiber nerve problems that can cause pain, temperature-related nerve symptoms, or body-function nerve issues. It aims to understand how these nerve problems affect quality of life and medical needs, and compare them with people without neuropathy.
ParisAges 18 years+ - NCT06593041Recruiting
Platelets in lupus and other autoimmune diseases
This study looks at how platelets (small blood cells that help with clotting) might play a role in autoimmune diseases like lupus. By understanding this, researchers hope to find new ways to treat these conditions.
Strasbourg, FranceAges 18–70 - NCT07246096RecruitingEarly Phase 1
CAR-T cell therapy for autoimmune diseases
This trial tests a new CAR-T cell treatment for people with certain autoimmune diseases that have not responded to standard therapies. The treatment uses your own immune cells modified to target and attack disease-causing cells.
ShanghaiAges 18–70 - NCT07062523RecruitingPhase 1/Phase 2
FAPI PET scan for Sjögren's syndrome inflammation
This study uses a special PET scan (FAPI PET) to look at inflammation in people with Sjögren's syndrome. It helps doctors understand how active the disease is. You may join if you have Sjögren's syndrome or a solid tumor that needs this scan, and you are not on certain medications.
BeijingAges 18–80 - NCT06979531RecruitingPhase 2
A study of IMVT-1402 for Sjogren's disease with moderate to severe symptoms
This trial tests an experimental drug, IMVT-1402, in adults with primary Sjogren's disease who have moderate to severe symptoms. The goal is to see if it can reduce disease activity safely.
Covina, CaliforniaAges 18–74 - NCT03040583Recruiting
Study of people with primary Sjögren’s syndrome
This study follows adults with primary Sjögren’s syndrome. It may help researchers understand the condition better by using information from people who have already joined the earlier ASSESS study.
Le Kremlin-Bicêtre, Val De MarneAges 18 years+ - NCT07361094RecruitingPhase 1
CAR-T therapy for autoimmune disease after prior treatment
This trial tests a new CAR-T cell therapy that targets two proteins (CD19 and BCMA) on immune cells. It is for people with certain autoimmune diseases (like lupus or scleroderma) that have not responded well to standard treatments or have relapsed after prior cell therapy.
BeijingAges 18–70
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Common questions
- Are there clinical trials for sjögren's syndrome?
- Yes. Clin2 currently lists 29 recruiting sjögren's syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a sjögren's syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a sjögren's syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.