Clinical trials · California
Syphilis clinical trials in California
We’re tracking 4 recruiting syphilis studies with a site in California — including Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT07089836Recruiting
Syphilis blood test study for at-risk and healthy people
This study tests two new blood tests for syphilis. It compares them to approved tests using blood from people who may have or had syphilis, including pregnant women, HIV-positive people, and healthy volunteers.
Lancaster, CaliforniaAges 13 years+ - NCT06082453Recruiting
Modernizing syphilis testing in pregnancy and beyond
This study is testing a new, faster way to check for syphilis in pregnant people, new mothers, and their newborns, as well as in men and non-pregnant people at a Harris Health clinic. The goal is to make sure more people get the right treatment quickly.
Los Angeles, CaliforniaAges Up to 45 years - NCT04958122RecruitingPhase 3
Antibiotic treatment trial for early syphilis
This Phase 3 study tests whether cefixime can treat primary, secondary, or early latent syphilis. It may help by offering another effective antibiotic option, including for some people who also have HIV (if well controlled).
Los Angeles, CaliforniaAges 18 years+ - NCT06738407RecruitingPhase 4
Doxycycline to prevent STIs in high-risk people
This study tests whether taking a daily antibiotic (doxycycline) can prevent sexually transmitted infections in people at high risk. If you've had an STI recently and sometimes have sex without condoms, you might be able to join.
Los Angeles, CaliforniaAges 13–29
Syphilis trials by city in California
Where these studies are running in California
Institutions with a site for the recruiting syphilis studies listed above.
- University of Southern California · 2 studies
- Chemidox Clinical Trials
- Folio Clinical Research
- San Francisco Department of Public Health
- UCLA Care
- University of California, Los Angeles (UCLA)
What taking part in a syphilis study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Syphilis trials in other states
Common questions
- Are there syphilis clinical trials in California?
- Yes. We're currently tracking 4 recruiting syphilis studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a syphilis study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a syphilis trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New syphilis studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.