Clinical trials · Boston, MA
Systemic Sclerosis clinical trials in Boston
We’re tracking 9 recruiting systemic sclerosis studies with a site in or near Boston — including Phase 1, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Boston
- NCT06655896RecruitingPhase 2
Rapcabtagene Autoleucel for severe diffuse scleroderma
This trial tests an investigational cell therapy called rapcabtagene autoleucel for people with severe diffuse cutaneous systemic sclerosis (a type of scleroderma that affects the skin and internal organs). The treatment uses your own modified immune cells to potentially calm the disease activity.
Boston, MassachusettsAges 18–70 - NCT05869955RecruitingPhase 1
CAR T cell therapy for severe autoimmune diseases
This early-phase study tests an experimental immune-cell treatment that targets a protein called CD-19 to calm severe, treatment-resistant autoimmune disease. It may help people whose lupus, inflammatory muscle disease, skin/scarring lung disease, or rheumatoid arthritis are not controlled by standard medicines.
Boston, MassachusettsAges 18 years+ - NCT06925542RecruitingPhase 1
Study of CTX112 for adults with autoimmune disease
This trial tests an experimental cell therapy called CTX112 for people with lupus, scleroderma, or inflammatory myositis that hasn't responded well to standard treatments. The goal is to see if it's safe and if it can help control the disease.
Boston, MassachusettsAges 18–70 - NCT05724173Recruiting
Test of a brain-to-computer device for ALS hand paralysis
This study checks whether a brain-computer interface (a BrainGate2 system) is safe and workable for people with ALS. If you qualify, you may be asked to try the device and complete study tasks to help researchers learn how well it can support communication or control.
Boston, MassachusettsAges 18–80 - NCT07497087RecruitingPhase 3
Study of nerandomilast for people with systemic sclerosis
This trial tests if nerandomilast can help people with systemic sclerosis, a disease that can affect the skin and lungs. It may be an option for those with active disease and reduced lung function.
Boston, MassachusettsAges 18 years+ - NCT07287670RecruitingPhase 2
Testing MTX-474 for diffuse scleroderma
This trial tests an investigational drug called MTX-474 for people with diffuse cutaneous systemic sclerosis (a type of scleroderma that affects the skin and internal organs). The study aims to see if it can help slow or improve skin thickening and other symptoms.
Boston, MassachusettsAges 18 years+ - NCT03816345RecruitingPhase 1
Nivolumab for advanced cancer with autoimmune conditions
This Phase 1 study tests nivolumab, an immunotherapy “anti-cancer accelerator,” in people with advanced cancer who also have an autoimmune disorder. It aims to see if nivolumab can be given safely and whether it may help shrink or control cancer.
Boston, MassachusettsAges 18 years+ - NCT00912041Recruiting
Test of a brain-to-computer device for quadriplegia
This study tests whether a tiny brain computer interface can help people with quadriplegia (loss of movement in all four limbs) communicate or control technology. It’s mainly a feasibility study, meaning the goal is to see if the device can work safely and reliably in real life.
Boston, MassachusettsAges 18–80 - NCT07335562RecruitingPhase 3
Comparing a new cell therapy (zola-cel) to standard care for active systemic sclerosis
This study tests a new type of cell therapy (CAR T-cells) to see if it works better than current treatments for active systemic sclerosis. It is designed for people whose lung disease is not well controlled by standard therapy.
Worcester, MassachusettsAges 16 years+
Hear when a new Systemic Sclerosis trial opens near Boston, MA
We’ll email you when one opens near Boston, MA — at most once a week, no account needed, unsubscribe anytime.
Systemic Sclerosis trials in other cities
Where these studies are running near Boston
Institutions with a site for the recruiting systemic sclerosis studies listed above.
- Massachusetts General Hospital · 4 studies
- Boston Medical Center · 3 studies
- Brigham and Women's Hospital
- Dana-Farber Cancer Institute
- Local Institution
- Local Institution - 0033
- Local Institution - 0038
- Providence VA Medical Center
What taking part in a systemic sclerosis study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting systemic sclerosis studies in Massachusetts.
Common questions
- Are there systemic sclerosis clinical trials near Boston?
- Yes. We're currently tracking 9 recruiting systemic sclerosis studies with a site near Boston, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a systemic sclerosis study near Boston?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Boston to take part?
- Not necessarily. These studies have a site near Boston, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a systemic sclerosis trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New systemic sclerosis studies open near Boston regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.