Clinical trials · California
Trauma clinical trials in California
We’re tracking 25 recruiting trauma studies with a site in California — including Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT05910567Recruiting
Ultrasound test for abdominal injuries in children after blunt trauma
This study looks at how well an abdominal ultrasound test (FAST) works for children who come to the emergency department after a serious blunt injury to the belly or torso. The goal is to help doctors find dangerous internal bleeding or organ injury quickly and safely.
Sacramento, CaliforniaAges Up to 17 years - NCT07129590Recruiting
Trauma-informed care to help pregnant people quit smoking
This study tests whether a trauma-informed care approach can help pregnant people who have experienced trauma to quit smoking. The study involves clinicians and patients working together to improve smoking cessation support.
San Francisco, CaliforniaAges 18 years+ - NCT04166877RecruitingPhase 4
Magnesium drip to reduce pain in ICU trauma patients
This trial tests whether a magnesium infusion can better control pain in adults who have serious injuries and need intensive care. It compares magnesium as part of pain treatment to standard pain care to see if pain improves and stays controlled.
Sacramento, CaliforniaAges 18 years+ - NCT05751863Recruiting
Sedation-first vs usual care in ventilated trauma patients
This study compares how pain medicine and calming medicine are started in critically injured (trauma) adults who are on a breathing machine. It aims to see whether a specific “analgesia-first” approach can improve comfort and support breathing weaning.
Long Beach, CaliforniaAges 18 years+ - NCT07301177Recruiting
Magnetic stimulation for veterans with nerve pain after injury
This study tests whether a non-invasive magnetic stimulation treatment can help veterans with long-term nerve pain after an injury or surgery. It may offer a drug-free option to reduce pain and improve quality of life.
San Diego, CaliforniaAges 18 years+ - NCT07346638Recruiting
Trauma therapy for women with suicidal thoughts
This trial tests a group therapy program called BEAR for women who have experienced trauma and are currently having suicidal thoughts. The program aims to help reduce distress and improve coping.
Stanford, CaliforniaAges 18–75 - NCT06629064Recruiting
Memory training for PTSD symptoms
This study tests a computer-based memory training program for people with PTSD. It aims to see if this training can help reduce PTSD symptoms by improving how your brain processes memories. The study involves 8 remote sessions over 4 weeks and two MRI scans to look at brain changes.
San Diego, CaliforniaAges 18–65 - NCT05958342RecruitingPhase 2
Calcium and vasopressin for bleeding shock after major injury
This trial tests whether giving calcium and vasopressin early can improve outcomes in people with major injury who are at risk for life-threatening bleeding shock. It mainly includes patients who need rapid blood transfusion and likely major surgery to stop bleeding.
San Francisco, CaliforniaAges 18–90 - NCT04712461Recruiting
Support program to reduce therapist burnout
This trial tests whether adding specific implementation supports can reduce burnout in therapists who provide evidence-based care for children who have experienced trauma. It may help therapists feel more supported while delivering these child trauma treatments.
San Diego, CaliforniaAges 3–99 - NCT04678154RecruitingPhase 3
Antibiotic trial for severe open fractures of the leg or foot
This trial tests a new way of giving antibiotics to people with severe open fractures in the leg, ankle, or foot. The goal is to see if it helps prevent infections after surgery.
Redwood City, CaliforniaAges 18–64 - NCT05856370Recruiting
Study for follow-up of Medtronic spine or skull devices
This study checks how well certain Medtronic devices for the skull or spine are working in real-world care. If you’re getting one of these devices, you may be asked to do scheduled follow-up visits and assessments to confirm safety and performance.
Sacramento, CaliforniaAges 18 years+ - NCT07219290Enrolling by invitation
Lung function study based on birth order in the litter
This study looks at how your lung function might be related to your position in your mother's litter. It may help us understand more about breathing health.
Fresno, CaliforniaAges 18–65 - NCT04937868Recruiting
Guiding CT scans for belly and pelvis injuries after blunt trauma
This study looks at how to make a better decision tool for when to order a CT scan of the belly and pelvis after a blunt injury in the emergency department. It aims to help clinicians choose the right patients for imaging during the first evaluation.
Los Angeles, CaliforniaAges Any age - NCT05638581RecruitingPhase 3
Compare low-titer type O whole blood for trauma bleeding
This study tests whether giving low-titer type O whole blood (or related blood products) works better for treating serious bleeding after a traumatic injury. It’s for adults who start blood transfusions right away under a massive bleeding plan.
Los Angeles, CaliforniaAges 15 years+ - NCT05683132Recruiting
Therapy to improve sleep in women with PTSD symptoms
This study is testing treatment approaches for improving insomnia (trouble sleeping) in women Veterans who also have PTSD symptoms. It may help reduce sleep problems and improve day-to-day functioning.
West Los Angeles, CaliforniaAges 18 years+ - NCT06070350RecruitingPhase 3
Massive transfusion for life-threatening bleeding in children
This study tests whether adding the drug tranexamic acid (TXA) to a massive blood transfusion helps control life-threatening bleeding in children who are severely injured. It compares two groups: one gets TXA and the other gets a placebo (a dummy drug with no active ingredient).
Sacramento, CaliforniaAges Up to 17 years - NCT06175104Recruiting
HeartGPS: Support for parents after a prenatal heart diagnosis
This study tests a counseling program for parents whose unborn baby has a serious heart condition called single ventricle. The program aims to help parents manage stress and support their baby's development before and after birth.
Los Angeles, CaliforniaAges 18 years+ - NCT06216600Recruiting
Women's strength and resilience program for HIV and substance use
This study tests a program for women living with HIV who also struggle with substance use or heavy drinking. It combines exercise and support to help build strength and resilience. You may qualify if you've missed some HIV medications, have a detectable viral load, and have experienced violence.
San Diego, CaliforniaAges 18 years+ - NCT06293469Recruiting
Speeding up flap surgery for severe leg injuries
This trial tests whether performing flap surgery sooner after a severe leg injury below the knee leads to better outcomes. If you have an open fracture or dislocation that needs a flap, you may be able to join.
Sacramento, CaliforniaAges 18 years+ - NCT06370520Recruiting
Teen emotions screening after mild brain injury
This study screens teens aged 11 to 17 for emotional and mental health problems after a mild traumatic brain injury (mTBI, also called concussion or minor head injury). The goal is to find out if the hospital screening helps identify teens who may need extra support.
Sacramento, CaliforniaAges 11–17 - NCT06413173Recruiting
Remote brain stimulation for attention after mild TBI
This trial tests if a remote brain stimulation device can improve attention and concentration in active-duty service members who have had a mild traumatic brain injury. Participants use the device at home while completing tasks to help with daily focus.
San Diego, CaliforniaAges 18–60 - NCT06742801Recruiting
Onyx liquid embolic for active bleeding outside the brain and heart
This trial tests a liquid material called Onyx that is injected into blood vessels to stop active bleeding in areas like the arms, legs, belly, or chest. It may help people with uncontrolled bleeding that needs to be blocked quickly.
Irvine, CaliforniaAges 22 years+ - NCT06328010Enrolling by invitation
Real-world data registry for wound care treatments
This study collects information on various wound types and how they respond to standard care. It aims to learn what works best for wounds that haven't healed after 4 weeks of treatment.
Riverside, CaliforniaAges 18 years+ - NCT06069154Enrolling by invitation
Freezing nerves for rib fracture pain
This study tests a procedure called cryoneurolysis, which uses cold to temporarily freeze nerves near broken ribs to relieve pain. It is for adults who have 1 to 6 recently broken ribs with at least moderate pain and are already getting a nerve block injection.
La Jolla, CaliforniaAges 18 years+
Where these studies are running in California
Institutions with a site for the recruiting trauma studies listed above.
- University of California, Davis Medical Center · 6 studies
- Stanford University · 2 studies
- University of California, San Francisco · 2 studies
- Zuckerberg San Francisco General Hospital and Trauma Center · 2 studies
- Children's Hospital Los Angeles
- Long Beach Memorial Medical Center
- Naval Medical Center San Diego
- San Diego State University
What taking part in a trauma study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Trauma trials in other states
Common questions
- Are there trauma clinical trials in California?
- Yes. We're currently tracking 25 recruiting trauma studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a trauma study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a trauma trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New trauma studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.