Sedation-first vs usual care in ventilated trauma patients
Part of Brain & nervous system, Injuries & trauma, Lungs & breathing clinical trials.
This study compares how pain medicine and calming medicine are started in critically injured (trauma) adults who are on a breathing machine. It aims to see whether a specific “analgesia-first” approach can improve comfort and support breathing weaning.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You are on a breathing machine and doctors expect you’ll need it for at least 48 hours
- The ICU team has started a continuous pain/sedation medicine through an IV
- Your medical team thinks you may be able to come off the breathing machine soon
- You are not being treated with medicines that fully paralyze muscles (neuromuscular blocking agents)
- You do not have an allergy to midazolam, lorazepam, and/or propofol
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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