Clinical trials · Cleveland, OH
Treatment Resistant Depression clinical trials in Cleveland
We’re tracking 3 recruiting treatment resistant depression studies with a site in or near Cleveland — including Phase 2 studies, each written for real people, not researchers.
Recruiting studies near Cleveland
- NCT03887715RecruitingTeam says not enrolling
VNS device for long-term depression that hasn’t improved
This trial studies whether a vagus nerve stimulation (VNS) device can reduce symptoms of treatment-resistant depression. Participants either receive the VNS treatment or a no-stimulation control, to compare safety and effectiveness.
Cleveland, OhioAges 18 years+ - NCT06423430Recruiting
Deep brain stimulation for treatment-resistant depression (TRANSCEND)
This trial tests a new brain stimulation treatment (deep brain stimulation, or DBS) for people with hard-to-treat depression. It aims to see if targeting a specific brain area can help when other treatments have failed.
Cleveland, OhioAges 22–70 - NCT07553637RecruitingPhase 2
ALTO-207 for Adults With Hard-to-Treat Depression
This study tests whether a new medication called ALTO-207 can help people with depression that hasn't improved with standard antidepressants. You may qualify if you've tried multiple antidepressants without enough relief and are willing to add this experimental treatment to your current medication.
Garfield Heights, OhioAges 18–75
Hear when a new Treatment Resistant Depression trial opens near Cleveland, OH
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Treatment Resistant Depression trials in other cities
Where these studies are running near Cleveland
Institutions with a site for the recruiting treatment resistant depression studies listed above.
- Charak Center for Health and Wellness
- Cleveland Clinic
- Signature Research Associates, Inc.
- Site 7158
- University Hospitals Cleveland Medical Center
What taking part in a treatment resistant depression study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting treatment resistant depression studies in Ohio.
Common questions
- Are there treatment resistant depression clinical trials near Cleveland?
- Yes. We're currently tracking 3 recruiting treatment resistant depression studies with a site near Cleveland, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a treatment resistant depression study near Cleveland?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Cleveland to take part?
- Not necessarily. These studies have a site near Cleveland, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a treatment resistant depression trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New treatment resistant depression studies open near Cleveland regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.