Clinical trials · Indiana
Treatment Resistant Depression clinical trials in Indiana
We’re tracking 5 recruiting treatment resistant depression studies with a site in Indiana — including Phase 2 studies, each written for real people, not researchers.
Recruiting studies in Indiana
- NCT03887715RecruitingTeam says not enrolling
VNS device for long-term depression that hasn’t improved
This trial studies whether a vagus nerve stimulation (VNS) device can reduce symptoms of treatment-resistant depression. Participants either receive the VNS treatment or a no-stimulation control, to compare safety and effectiveness.
South Bend, IndianaAges 18 years+ - NCT06423430Recruiting
Deep brain stimulation for treatment-resistant depression (TRANSCEND)
This trial tests a new brain stimulation treatment (deep brain stimulation, or DBS) for people with hard-to-treat depression. It aims to see if targeting a specific brain area can help when other treatments have failed.
Indianapolis, IndianaAges 22–70 - NCT06511544Recruiting
Brain stimulation for treatment-resistant depression with rumination
This study tests whether a specific form of brain stimulation (called rTMS) can help people with treatment-resistant depression by targeting brain circuits linked to rumination (repetitive negative thinking). If you have tried at least one antidepressant without success and do not have other major mental health conditions, this trial may be worth exploring with your doctor.
Indianapolis, IndianaAges 18–70 - NCT07553637RecruitingPhase 2
ALTO-207 for Adults With Hard-to-Treat Depression
This study tests whether a new medication called ALTO-207 can help people with depression that hasn't improved with standard antidepressants. You may qualify if you've tried multiple antidepressants without enough relief and are willing to add this experimental treatment to your current medication.
Indianapolis, IndianaAges 18–75 - NCT07226128Recruiting
Can therapy help HIV patients with depression and insulin resistance?
This study tests if cognitive behavioral therapy (a type of talk therapy) can improve how your body handles sugar (insulin resistance) for people living with HIV who also have depression. You may join if you have HIV, are on stable HIV meds, feel depressed, and do not have diabetes.
Indianapolis, IndianaAges 18 years+
Treatment Resistant Depression trials by city in Indiana
Where these studies are running in Indiana
Institutions with a site for the recruiting treatment resistant depression studies listed above.
- Advanced Research Institute, Inc.
- Beacon Medical Group Behavioral Health
- Goodman Hall
- Indiana University Health
- Indiana University School of Medicine
- Site 7169
What taking part in a treatment resistant depression study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Treatment Resistant Depression trials in other states
Common questions
- Are there treatment resistant depression clinical trials in Indiana?
- Yes. We're currently tracking 5 recruiting treatment resistant depression studies with a site in Indiana, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a treatment resistant depression study in Indiana?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Indiana to take part?
- Not necessarily. These studies have a site in Indiana, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a treatment resistant depression trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New treatment resistant depression studies open in Indiana regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.