Clinical trials
Type 2 diabetes clinical trials
A condition where the body can’t use insulin properly, raising blood sugar. We’re tracking 1,079 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT02000687Recruiting
Long-term follow-up after islet transplant graft failure
This study follows people over the long term after their islet transplant fully stops working. It aims to learn what happens after complete graft loss and monitor health outcomes over time.
Miami, FloridaAges 18–75 - NCT00097292Recruiting
Preventing Type 1 Diabetes in At-Risk People
This study looks for people at high risk of developing type 1 diabetes (based on family history or blood markers) and follows them over time to understand disease development. The goal is to eventually prevent or delay type 1 diabetes in people who don't have it yet.
Orange, CaliforniaAges 2–45 - NCT01999374Recruiting
Long-term follow-up for people with transplanted islet cells
This study checks how well transplanted islet cells are working over time and monitors long-term safety. If you previously received an islet transplant and are still using medicine to prevent rejection, you may be followed again.
Miami, FloridaAges 18–65 - NCT01999361Recruiting
Prevent new immune reaction after islet transplant failure
This study looks at ways to prevent the body from developing a new harmful immune reaction after an islet transplant no longer works. It may help people who have already lost a transplanted islet graft from getting harder-to-treat immune responses later.
Miami, FloridaAges 18–70 - NCT05498116RecruitingPhase 4
Montelukast to improve kidney and blood vessel function in type 1 diabetes
This trial tests whether montelukast, a medicine commonly used for allergies, can improve kidney health and blood vessel function in adults with long-term type 1 diabetes. You may join a treatment group and have kidney and circulation measurements taken over the study period.
Aurora, ColoradoAges 18–80 - NCT07507708Recruiting
Smart insulin system with behavior support for type 1 diabetes
This study tests a smart insulin pump and continuous glucose monitor system that adjusts insulin automatically and uses behavior support to improve blood sugar control. It's for people with type 1 diabetes who have used an approved automated insulin delivery system recently and are willing to use study devices.
Charlottesville, VirginiaAges 18 years+ - NCT07634770RecruitingPhase 1
Oral insulin study compared to injected insulin
This early-stage study tests whether a new oral (swallowed) form of insulin called SCD0503 works as well as regular injected insulin in men with type 1 diabetes. Researchers will also check how food affects how your body absorbs the oral insulin.
Neuss, North Rhine-WestphaliaAges 18–64 - NCT07143773RecruitingPhase 4
SGLT2i safety in kidney transplant patients without diabetes
This study tests whether a medicine called SGLT2i (a type of pill for kidney health) is safe and helpful for kidney transplant recipients who do not have diabetes. It aims to see if it can improve how the new kidney works.
OdenseAges 18 years+ - NCT07396376RecruitingPhase 1/Phase 2
Testing ELU42 spray for diabetic foot ulcers
This study tests a new topical spray (ELU42) to help heal diabetic foot ulcers. It may be a good option if you have a non-infected, non-ischemic ulcer and your blood sugar is reasonably controlled.
O'Fallon, IllinoisAges 18–75 - NCT07279194RecruitingPhase 3
Study of HDM1005 for weight loss in Chinese adults without diabetes
This trial tests a new medication, HDM1005, to help people with obesity or overweight who do not have diabetes lose weight. It is for Chinese adults who have a high body mass index (BMI) or a BMI above 24 with weight-related health problems like high blood pressure or fatty liver.
ShanghaiAges 18 years+ - NCT05326204Recruiting
Compare one vs two hours of blood sugar checks
This trial tests whether checking your blood sugar one hour after meals works just as well as checking two hours after meals for people with gestational diabetes who are already on treatment. It may help simplify monitoring and improve how safely diabetes is managed during pregnancy.
Kuala Lumpur, W.PersekutuanAges 18–45 - NCT06942520RecruitingPhase 2
Gene therapy for diabetic macular edema in adults
This trial tests a gene therapy called RGX-314 for people with diabetic macular edema that affects the center of the vision. If you have had previous treatment and still have swelling, this study may be an option.
Reno, NevadaAges 25–89 - NCT04422366RecruitingPhase 3
9-valent HPV vaccine study for healthy Chinese women
This trial tests a 9-type HPV vaccine to see how well it works, how it helps the body build protection, and whether it’s safe. It’s for healthy Chinese women who have not had HPV vaccination before and meet specific health and timing requirements.
Liuzhou, GuangxiAges 20–45 - NCT06896799Recruiting
Food order and blood sugar in gestational diabetes
This study looks at whether the order in which you eat foods during a meal can help control your blood sugar levels. It might help you manage your gestational diabetes better through diet alone.
BelfastAges 18–50 - NCT07521631RecruitingPhase 2
HDM1005 versus Tirzepatide for weight management in obese adults
This study tests whether a new injectable medication called HDM1005 works as well as tirzepatide (a GLP-1 drug) for weight loss in adults with obesity but no diabetes. Both medications work similarly in the body to help control appetite and weight.
ShanghaiAges 18–65 - NCT06065852Recruiting
National registry for rare kidney diseases
This study creates a registry to collect health information from people with rare kidney diseases. It aims to improve understanding and future treatments by tracking patient experiences.
Bristol, South WestAges Any age - NCT06708260RecruitingPhase 2
Study of ENN0403 for diabetic macular edema
This trial tests a new eye drop or injection called ENN0403 for people with diabetic macular edema (swelling in the back of the eye due to diabetes). The goal is to see if it can improve vision and reduce swelling.
Tianjin, Tianjin MunicipalityAges 18–80 - NCT06528405RecruitingPhase 2
SGLT2 inhibitor study for acute kidney disease patients
This study tests whether SGLT2 inhibitors (a type of diabetes drug that also helps kidneys) can help patients with acute kidney disease. It may be an option if you have diabetes or chronic kidney disease along with acute kidney problems.
TaipeiAges 18–80 - NCT06145308RecruitingPhase 2
Precision treatment for salivary gland cancer
This trial tests a personalized treatment approach for recurrent or metastatic salivary gland cancer. It uses special tests on your tumor to find the best targeted therapy for your specific cancer type.
Beijing, Beijing MunicipalityAges 18–100 - NCT05548205Recruiting
Glucose monitoring for people starting insulin after hospital discharge
This study checks whether using a continuous glucose monitor for 2 weeks after you leave the hospital helps you manage blood sugar better when you are newly starting insulin. It may help your care team adjust insulin and track glucose trends more closely right after discharge.
Mineola, New YorkAges 18–100 - NCT04286399RecruitingPhase 4
Prevention trial for heart outcomes in people with type 2 diabetes
This Phase 4 trial studies an approach to help prevent heart problems in adults with type 2 diabetes who are at higher heart risk. It may help reduce future cardiovascular events by testing medications for safety and benefit in this group.
SingaporeAges 40 years+ - NCT06618612Recruiting
Wound matrix for diabetic foot ulcers
This study tests if a special wound dressing (collagen matrix with antimicrobial) plus standard care helps diabetic foot ulcers heal better than standard care alone. It's for people with diabetes who have a foot sore that hasn't healed for at least 4 weeks.
Clevland, OhioAges 18 years+ - NCT06328010Enrolling by invitation
Real-world data registry for wound care treatments
This study collects information on various wound types and how they respond to standard care. It aims to learn what works best for wounds that haven't healed after 4 weeks of treatment.
Scottsdale, ArizonaAges 18 years+
Hear when a new Type 2 diabetes trial opens
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Common questions
- Are there clinical trials for type 2 diabetes?
- Yes. Clin2 currently lists 1,079 recruiting type 2 diabetes studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a type 2 diabetes trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a type 2 diabetes trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.