Clinical trials
Type 2 Diabetes (T2DM) clinical trials
Below are recruiting type 2 diabetes (t2dm) clinical trials, each written for real people, not researchers. We’re tracking 232 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07606066Recruiting
Finding Type 2 Diabetes Patients for Future Research Studies
This is a screening study to identify and understand people with type 2 diabetes whose blood sugar isn't well controlled, so they can potentially join future diabetes research trials. You won't receive a new treatment in this study—it's about getting to know your health history and seeing if you might be a good fit for upcoming studies.
Peoria, ArizonaAges 18 years+ - NCT07064473RecruitingPhase 3
Testing vicadrostat plus empagliflozin for diabetes, high blood pressure, and heart disease
This study tests a new pill called vicadrostat taken with another medicine (empagliflozin) to see if it helps people with type 2 diabetes, high blood pressure, and heart disease. It may reduce the risk of heart problems, but you must not have had heart failure or use certain other heart medications.
Anniston, AlabamaAges 18 years+ - NCT07563699RecruitingPhase 1/Phase 2
Long-acting semaglutide injection for type 2 diabetes
This study tests a new long-acting form of semaglutide (a diabetes medication you may already take weekly) given as a depot injection. Researchers want to see if this new form is safe and works better for managing type 2 diabetes.
Tel AvivAges 18–64 - NCT07606872Enrolling by invitation
Testing a diabetes score to guide treatment reversal
This study tests a new scoring system to help people with type 2 diabetes understand their condition better and potentially reverse or improve it. You'll use a digital platform to track blood sugar, answer health questions, and have blood tests to see if the system helps guide your treatment plan.
Manchester, EnglandAges 18 years+ - NCT07448974RecruitingPhase 3
Vitamin D for Preventing Type 2 Diabetes
This study tests if taking extra vitamin D can help people with prediabetes keep their blood sugar in a healthy range and lower the chance of developing type 2 diabetes. Participants will take high-dose or standard vitamin D and be monitored for about 2 years.
Boston, MassachusettsAges 30–74 - NCT07149610Recruiting
Connected care for type 2 diabetes self-management
This study tests a connected care program to help people with type 2 diabetes manage their condition better using a smartphone. It may help you if your blood sugar is not well controlled and you live in the Marche region of Italy.
Ancona, AnconaAges 18 years+ - NCT07527650RecruitingPhase 2
Testing HM15275 for Type 2 Diabetes Management
This study tests a new medication called HM15275 to help control blood sugar in people with type 2 diabetes. The trial will check if the medication works well and is safe when added to diet, exercise, or metformin treatment.
Mesa, ArizonaAges 18–75 - NCT07743450RecruitingPhase 3
Once-daily pill for weight loss in people with type 2 diabetes
This study tests an oral medication, ASC30, to see if it helps people with type 2 diabetes who are overweight or obese lose weight and improve blood sugar control. It is a once-daily pill that may offer a new treatment option.
Birmingham, AlabamaAges 18 years+ - NCT07463209Recruiting
Diabetes education with continuous glucose monitoring for older adults
This study tests whether adding continuous glucose monitoring (CGM) to diabetes education helps older adults with diabetes manage their blood sugar better. You and a care partner will learn how to use CGM and support each other.
Chapel Hill, North CarolinaAges 65 years+ - NCT07351058RecruitingPhase 3
Enicepatide for weight loss in people with type 2 diabetes
This trial tests an investigational medication, Enicepatide, to see if it helps people with obesity or overweight and type 2 diabetes lose weight and improve blood sugar control. You will receive weekly injections and regular check-ups.
Guntersville, AlabamaAges 18 years+ - NCT07670416RecruitingPhase 3
A study of enicepatide for people with obesity or overweight
This trial tests if enicepatide can help people with obesity or overweight lose weight, including those with or without type 2 diabetes. It aims to see if the drug is safe and effective.
Zhengzhou, HenanAges 18 years+ - NCT07757308Recruiting
Brain and heart connection in type 2 diabetes
This study looks at how type 2 diabetes affects the link between your brain and heart. Participants will undergo tests of memory, thinking, and heart function to see how these are related in diabetes.
TunceliAges 40–75 - NCT06830096Recruiting
Understanding a key cell channel in type 2 diabetes
This study looks at how a specific channel in your cells (called the KATP channel) affects blood sugar control in people with and without type 2 diabetes. It aims to understand why some people develop diabetes and how to better treat it.
St Louis, MissouriAges 18–65 - NCT07599410RecruitingPhase 2
Testing HRS9531 for Type 2 Diabetes Blood Sugar Control
This study tests whether a new tablet called HRS9531 helps people with type 2 diabetes control their blood sugar better. You would take it along with your current diabetes management (lifestyle changes or metformin) over several months.
Beijing, Beijing MunicipalityAges 18–70 - NCT07660445Recruiting
Endoscopic stomach reshaping and duodenal procedure for obese type 2 diabetes
This trial tests a procedure that reshapes the stomach and treats the upper intestine to help control blood sugar and weight in people with obesity and type 2 diabetes. It may be an option if you have a moderate to high need for metabolic surgery.
ShatinAges 18–70 - NCT07019012RecruitingPhase 4
Testing a new every-2-week pill for type 2 diabetes
This study tests a new once-every-2-weeks pill (cofrogliptin) added to your current diabetes medications (metformin and dapagliflozin) compared to a daily pill (linagliptin). It may help improve blood sugar control with fewer daily pills.
Wuhan, HubeiAges 18 years+ - NCT06562907RecruitingPhase 1
Study of GS-4571 in healthy people, people with obesity, and people with type 2 diabetes
This trial tests an experimental drug called GS-4571 in three groups: healthy individuals, people with obesity (but not diabetes), and people with type 2 diabetes who are not obese. The study aims to see how the drug affects the body and how safe it is.
Miami, FloridaAges 18–55 - NCT07496177RecruitingPhase 2
HTD1801 for kidney function in diabetes and kidney disease
This trial tests whether a new drug, HTD1801, can protect or improve kidney function in people with type 2 diabetes and chronic kidney disease. It may help slow kidney damage and reduce protein in urine.
Weifang, ShandongAges 18–75 - NCT07347080RecruitingEarly Phase 1
Study of a new RNA-based drug for type 2 diabetes
This trial tests an experimental injection (CR059) for type 2 diabetes. It looks at safety and how the body handles different doses. You may qualify if you have had diabetes for 3 months to 5 years and are currently managing it with diet/exercise or certain diabetes pills.
Luoyang, HenanAges 18–65 - NCT06942195Recruiting
Calcium's effect on gut function and blood sugar in type 2 diabetes
This study tests if calcium can help control blood sugar and gut function in men with type 2 diabetes. You'll take calcium or a placebo and have a tube inserted into your stomach to measure digestion.
Adelaide, South AustraliaAges 18–70 - NCT07743983RecruitingPhase 3
Study of BGM0504 in Early Type 2 Diabetes with Obesity
This trial tests an investigational drug, BGM0504, for people recently diagnosed with type 2 diabetes who also have obesity. It aims to see if the drug can help control blood sugar and support weight loss.
Nanjing, JiangsuAges 18–75 - NCT07662109RecruitingPhase 3
Testing a new combo pill for type 2 diabetes
This study tests if a new medicine (elecoglipron) combined with dapagliflozin is safe and works better for adults with type 2 diabetes that isn't well controlled by diet or other medications.
Huntsville, AlabamaAges 18 years+ - NCT07187479Recruiting
Testing a new insulin approach for kidney disease and diabetes
This study tests a new approach to help your body use insulin better, which may improve blood sugar control and slow down kidney disease. It is for people with advanced chronic kidney disease and type 2 diabetes who are not yet on dialysis.
Phoenix, ArizonaAges 18 years+ - NCT07662044RecruitingPhase 3
Studying elecoglipron for type 2 diabetes
This trial tests a new medicine called elecoglipron, taken alone or with another diabetes drug (dapagliflozin), to see if it helps control blood sugar better than a placebo. It may be an option if your current treatment isn't working well enough.
Birmingham, AlabamaAges 18 years+
Hear when a new Type 2 Diabetes (T2DM) trial opens
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Common questions
- Are there clinical trials for type 2 diabetes (t2dm)?
- Yes. Clin2 currently lists 232 recruiting type 2 diabetes (t2dm) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a type 2 diabetes (t2dm) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a type 2 diabetes (t2dm) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.