Clinical trials
Vaping clinical trials
Below are recruiting vaping clinical trials, each written for real people, not researchers. We’re tracking 35 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07134426Recruiting
Vaped phenanthrene study for healthy adults
This study is testing a chemical called phenanthrene that is found in e-cigarette vapor. Researchers want to see how the body processes it, so they are looking for healthy people who have tried vaping.
Minneapolis, MinnesotaAges 21 years+ - NCT07040566RecruitingPhase 2
Varenicline to help stop vaping
This trial tests whether varenicline, a medicine that reduces cravings, can help people quit using e-cigarettes that contain nicotine. You must be a daily nicotine vaper and live in Connecticut or South Carolina.
New Haven, ConnecticutAges 18 years+ - NCT06944847Recruiting
Vaping and smoking study for people with schizophrenia
This study looks at habits of vaping and smoking in people with schizophrenia. It may help researchers understand how to better support people who want to reduce or quit nicotine use.
Buffalo, New YorkAges 21–50 - NCT06804109Recruiting
Nerve stimulation and cognition in young adults who vape
This study tests whether a gentle, non-invasive nerve stimulation device (placed on the neck) can affect thinking and attention in young adults who vape. You'd attend a single session where you receive the stimulation or a placebo while doing simple computer tasks.
Philadelphia, PennsylvaniaAges 18–25 - NCT05906082Recruiting
Vape-free texting program for young adults in rural North Dakota
This pilot study tests whether vape-free coaching by text message can help people quit e-cigarettes. You may be eligible if you are a young adult who vapes daily and plans to quit within a month.
Milwaukee, WisconsinAges 18–24 - NCT06483412Enrolling by invitation
Healthy Futures: A Vaping Intervention for Teens
This study is testing a program called Healthy Futures that schools can use instead of suspending students caught vaping. The trial wants to see if the program helps teens quit vaping.
Palo Alto, CaliforniaAges 14–18 - NCT06448351Recruiting
Changing nicotine in e-cigarettes to reduce harm
This study tests how changing the amount of nicotine in e-cigarettes affects people's behavior. It looks at two groups: young adults who already vape and older adult smokers who want to try vaping, to see if different nicotine levels can help reduce smoking or make vaping safer.
Columbus, OhioAges 21–65 - NCT06260683Recruiting
Comparing tobacco vs. non-tobacco flavored e-cigarettes for quitting smoking
This study tests whether using e-cigarettes with a tobacco flavor or a non-tobacco flavor helps people who smoke switch away from regular cigarettes. Participants will use either e-cigarettes or nicotine replacement therapy for a period of time, and researchers will track their smoking behavior.
Columbus, OhioAges 21 years+ - NCT05999383RecruitingPhase 2
Marijuana and tobacco use study
This trial looks at how marijuana and tobacco work together in your body. If you regularly use both cannabis and tobacco, you may help researchers understand their combined effects.
San Francisco, CaliforniaAges 21–65 - NCT05962229RecruitingPhase 1
Testing how synthetic nicotine is processed in regular e-cig users
This Phase 1 study tests how a synthetic nicotine product is absorbed and how the body responds (so researchers can better understand nicotine effects and handling). You may be able to join if you’re generally healthy and regularly use e-cigarettes, but you’ll need to avoid certain medicines and nicotine products during the study.
San Francisco, CaliforniaAges 21–65 - NCT05772845Recruiting
Study of quitting support for vaping and smoking withdrawal
This study looks at nicotine withdrawal symptoms in people who vape and/or smoke regularly. It may help improve how quitting support is tailored, based on how participants respond during the withdrawal period.
Buffalo, New YorkAges 21–50
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Common questions
- Are there clinical trials for vaping?
- Yes. Clin2 currently lists 35 recruiting vaping studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a vaping trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a vaping trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.