Clinical trials
Vaping clinical trials
Below are recruiting vaping clinical trials, each written for real people, not researchers. We’re tracking 32 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06819969Recruiting
Long-term lung health in Canadian vapers and smokers
This study compares lung function and exercise capacity among different groups: people who vape, people who smoke cigarettes, and people who do neither. It aims to understand how vaping devices affect lungs over time.
Edmonton, AlbertaAges 12 years+ - NCT07348224Recruiting
Nicotine and nicotine-like products study
This trial tests how your body processes synthetic nicotine and nicotine-like substances when used in e-cigarettes. The goal is to understand how they work and how long they stay in your system.
BernAges 18 years+ - NCT07207850Recruiting
Parents helping teens quit vaping
This study tests a program where parents work together to help their teenager stop vaping. It is designed for teens who vape and a parent or guardian who wants to support them.
Omaha, NebraskaAges 15–18 - NCT06662305RecruitingPhase 2
KickNic! App to Help Teens Quit Vaping
This study tests a new smartphone app called KickNic! to help teens quit vaping. If you're a regular vaper aged 12-19 and want to stop, the app might give you the support you need.
New Haven, ConnecticutAges 12–19 - NCT07540780Recruiting
Social media support groups to help teens quit vaping
This study tests whether online support groups on social media can help teenagers stop vaping. You'd join a group with other teens your age working toward the same goal, with support from trained peer mentors.
San Francisco, CaliforniaAges 13 years+ - NCT05447325Recruiting
Brain scans to study vaping to smoking risk
This study uses brain imaging to better predict who might start smoking cigarettes and who might increase nicotine use among young adult e-cigarette (vaping) users. It may help researchers find early warning signals so support can be targeted sooner.
Athens, GeorgiaAges 18–29 - NCT06291597Recruiting
Vaping study: effects on lungs and heart
This study is looking at how daily vaping affects your lungs and heart over time. If you vape every day, researchers want to monitor your health to spot any early warning signs.
QuébecAges 18 years+ - NCT06765291Recruiting
Help for teens to quit or reduce vaping
This program is for teens aged 14 to 19 who vape at least once a week and want to quit or cut back. It tests a behavioral support approach to help them stop using nicotine vapes.
Boston, MassachusettsAges 14–19 - NCT07129265Enrolling by invitation
Understanding vape marketing study for youth
This study looks at how young people understand vape marketing. You might join a working group or a focus group to share your thoughts.
Boston, MassachusettsAges 13 years+ - NCT06734780Recruiting
Vaping and Crohn's disease return after surgery
This study looks at how vaping versus smoking tobacco affects the return of Crohn's disease after surgery. It may help doctors understand which habit is safer for people who have had their intestine reconnected.
Milan, MichiganAges 18 years+ - NCT07362069Enrolling by invitation
Virtual reality program to prevent teen vaping
This trial tests whether a virtual reality experience can help 8th graders avoid or stop using e-cigarettes. School staff will also learn how to support students' mental health.
New Haven, ConnecticutAges 12–15 - NCT06832098RecruitingPhase 3
Nicotine patch plus spray vs reducing nicotine to quit vaping
This study tests two ways to help you stop vaping: using a nicotine patch and mouth spray, or slowly lowering the nicotine in your vape. If you live in New Zealand, vape regularly, and are ready to quit, this trial may help you find the best method.
AucklandAges 16 years+ - NCT06885606Recruiting
Using brain stimulation to help reduce vaping
This study tests whether a gentle brain stimulation technique called transcranial direct current stimulation (tDCS) can help people who vape daily cut back. You would attend daily sessions for two weeks to see if it makes a difference.
Toronto, OntarioAges 18–65 - NCT06196489Recruiting
Quit vaping: program for young veterans
This trial tests a program to help young veterans quit vaping. You'll get support through your phone or computer to help you stop using nicotine.
San Diego, CaliforniaAges 18–30 - NCT07009509Recruiting
Yes-Can! program to prevent youth vaping
This study tests a program called YES-CAN! that aims to keep middle and high school students from starting to vape nicotine. If you are a student in grades 6-12, or an adult working in a school, you may be able to join.
Aurora, ColoradoAges 9 years+ - NCT06909500Recruiting
Vaping cessation app for young adults
This trial tests a smartphone app called ACT on Vaping to help young adults quit vaping. It may help you if you are ready to stop using e-cigarettes and want support through a digital tool.
Seattle, WashingtonAges 18–30 - NCT05454267Recruiting
Study early blood vessel changes from vaping
This study looks for early signs of blood vessel problems in people who vape and in healthy non-vapers. It may help researchers find ways to detect and prevent vaping-related vascular disease early.
Miami, FloridaAges 18–40 - NCT05994209RecruitingPhase 1
Testing social media to help people stop vaping
This study tests if using social media and digital tools can help people reduce or stop vaping. It's for people who vape daily and want to quit.
St Louis, MissouriAges 15–25 - NCT06448351Recruiting
Changing nicotine in e-cigarettes to reduce harm
This study tests how changing the amount of nicotine in e-cigarettes affects people's behavior. It looks at two groups: young adults who already vape and older adult smokers who want to try vaping, to see if different nicotine levels can help reduce smoking or make vaping safer.
Columbus, OhioAges 21–65 - NCT06804109Recruiting
Nerve stimulation and cognition in young adults who vape
This study tests whether a gentle, non-invasive nerve stimulation device (placed on the neck) can affect thinking and attention in young adults who vape. You'd attend a single session where you receive the stimulation or a placebo while doing simple computer tasks.
Philadelphia, PennsylvaniaAges 18–25 - NCT05772845Recruiting
Study of quitting support for vaping and smoking withdrawal
This study looks at nicotine withdrawal symptoms in people who vape and/or smoke regularly. It may help improve how quitting support is tailored, based on how participants respond during the withdrawal period.
Buffalo, New YorkAges 21–50 - NCT06297005Recruiting
E-cigarette use in pregnancy and child health study
This study looks at how using e-cigarettes during pregnancy might affect children's health. If you are pregnant, smoke or vape, or are a non-smoker, you may be able to join and help us learn more.
DublinAges 18–46 - NCT06260683Recruiting
Comparing tobacco vs. non-tobacco flavored e-cigarettes for quitting smoking
This study tests whether using e-cigarettes with a tobacco flavor or a non-tobacco flavor helps people who smoke switch away from regular cigarettes. Participants will use either e-cigarettes or nicotine replacement therapy for a period of time, and researchers will track their smoking behavior.
Columbus, OhioAges 21 years+ - NCT06944847Recruiting
Vaping and smoking study for people with schizophrenia
This study looks at habits of vaping and smoking in people with schizophrenia. It may help researchers understand how to better support people who want to reduce or quit nicotine use.
Buffalo, New YorkAges 21–50
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Vaping trials by city
Studies with a site in or near these metro areas.
Vaping trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for vaping?
- Yes. Clin2 currently lists 32 recruiting vaping studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a vaping trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a vaping trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.