Clinical trials
Nicotine Vaping clinical trials
Below are recruiting nicotine vaping clinical trials, each written for real people, not researchers. We’re tracking 17 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07348224Recruiting
Nicotine and nicotine-like products study
This trial tests how your body processes synthetic nicotine and nicotine-like substances when used in e-cigarettes. The goal is to understand how they work and how long they stay in your system.
BernAges 18 years+ - NCT06832098RecruitingPhase 3
Nicotine patch plus spray vs reducing nicotine to quit vaping
This study tests two ways to help you stop vaping: using a nicotine patch and mouth spray, or slowly lowering the nicotine in your vape. If you live in New Zealand, vape regularly, and are ready to quit, this trial may help you find the best method.
AucklandAges 16 years+ - NCT07009509Recruiting
Yes-Can! program to prevent youth vaping
This study tests a program called YES-CAN! that aims to keep middle and high school students from starting to vape nicotine. If you are a student in grades 6-12, or an adult working in a school, you may be able to join.
Aurora, ColoradoAges 9 years+ - NCT05962229RecruitingPhase 1
Testing how synthetic nicotine is processed in regular e-cig users
This Phase 1 study tests how a synthetic nicotine product is absorbed and how the body responds (so researchers can better understand nicotine effects and handling). You may be able to join if you’re generally healthy and regularly use e-cigarettes, but you’ll need to avoid certain medicines and nicotine products during the study.
San Francisco, CaliforniaAges 21–65 - NCT05994209RecruitingPhase 1
Testing social media to help people stop vaping
This study tests if using social media and digital tools can help people reduce or stop vaping. It's for people who vape daily and want to quit.
St Louis, MissouriAges 15–25 - NCT07540780Recruiting
Social media support groups to help teens quit vaping
This study tests whether online support groups on social media can help teenagers stop vaping. You'd join a group with other teens your age working toward the same goal, with support from trained peer mentors.
San Francisco, CaliforniaAges 13 years+ - NCT06765291Recruiting
Help for teens to quit or reduce vaping
This program is for teens aged 14 to 19 who vape at least once a week and want to quit or cut back. It tests a behavioral support approach to help them stop using nicotine vapes.
Boston, MassachusettsAges 14–19 - NCT06662305RecruitingPhase 2
KickNic! App to Help Teens Quit Vaping
This study tests a new smartphone app called KickNic! to help teens quit vaping. If you're a regular vaper aged 12-19 and want to stop, the app might give you the support you need.
New Haven, ConnecticutAges 12–19 - NCT07129265Enrolling by invitation
Understanding vape marketing study for youth
This study looks at how young people understand vape marketing. You might join a working group or a focus group to share your thoughts.
Boston, MassachusettsAges 13 years+ - NCT07040566RecruitingPhase 2
Varenicline to help stop vaping
This trial tests whether varenicline, a medicine that reduces cravings, can help people quit using e-cigarettes that contain nicotine. You must be a daily nicotine vaper and live in Connecticut or South Carolina.
New Haven, ConnecticutAges 18 years+ - NCT05999383RecruitingPhase 2
Marijuana and tobacco use study
This trial looks at how marijuana and tobacco work together in your body. If you regularly use both cannabis and tobacco, you may help researchers understand their combined effects.
San Francisco, CaliforniaAges 21–65 - NCT07568483Recruiting
Web-based smoking cessation support program
This study tests TUBSIS 2.0, a digital program designed to help you quit or cut back on smoking. You'll use it on your computer, tablet, or phone, and researchers will track how it affects your smoking habits over time.
ZurichAges 18 years+ - NCT07145866RecruitingPhase 4
Varenicline and TMS for quitting nicotine use
This study tests whether combining the medication varenicline (Chantix) with a special brain stimulation treatment (TMS) can help people quit vaping or smoking nicotine. If you're motivated to quit and use nicotine daily, you may be able to join.
Boston, MassachusettsAges 18–65 - NCT06260683Recruiting
Comparing tobacco vs. non-tobacco flavored e-cigarettes for quitting smoking
This study tests whether using e-cigarettes with a tobacco flavor or a non-tobacco flavor helps people who smoke switch away from regular cigarettes. Participants will use either e-cigarettes or nicotine replacement therapy for a period of time, and researchers will track their smoking behavior.
Columbus, OhioAges 21 years+ - NCT06909500Recruiting
Vaping cessation app for young adults
This trial tests a smartphone app called ACT on Vaping to help young adults quit vaping. It may help you if you are ready to stop using e-cigarettes and want support through a digital tool.
Seattle, WashingtonAges 18–30 - NCT06448351Recruiting
Changing nicotine in e-cigarettes to reduce harm
This study tests how changing the amount of nicotine in e-cigarettes affects people's behavior. It looks at two groups: young adults who already vape and older adult smokers who want to try vaping, to see if different nicotine levels can help reduce smoking or make vaping safer.
Columbus, OhioAges 21–65 - NCT05447325Recruiting
Brain scans to study vaping to smoking risk
This study uses brain imaging to better predict who might start smoking cigarettes and who might increase nicotine use among young adult e-cigarette (vaping) users. It may help researchers find early warning signals so support can be targeted sooner.
Athens, GeorgiaAges 18–29
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Common questions
- Are there clinical trials for nicotine vaping?
- Yes. Clin2 currently lists 17 recruiting nicotine vaping studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a nicotine vaping trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a nicotine vaping trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.