Treatment
5-ALA clinical trials
We’re tracking 10 recruiting studies that include 5-ALA, each written for real people, not researchers, below.
Recruiting studies
- NCT01898416RecruitingPhase 2
5-ALA by mouth to reduce regrowth of desmoid tumors
This Phase 2 trial tests whether taking a medicine called 5-ALA by mouth after treatment can lower how often desmoid tumors come back in the same area. If you have a desmoid tumor that can be removed and you meet safety criteria, this study may help determine whether 5-ALA is effective and safe for you.
Tel Aviv, IsraelAges 18 years+ - NCT06160492RecruitingPhase 3
Testing a Glowing Dye to Improve Brain Tumor Removal
This trial compares two surgical techniques for removing malignant brain tumors: one using a special dye (5-ALA) that makes tumor cells glow under a blue light, versus the standard white light surgery. The goal is to see if the dye-guided approach helps surgeons remove more of the tumor safely.
Guangzhou, GuangdongAges 18–70 - NCT06948552RecruitingPhase 2
Using a light-sensitizing drug to find cancer in the upper urinary tract
This trial tests whether taking a drug called 5-ALA before a scope procedure helps doctors spot cancer cells in the upper urinary tract more clearly. If you are having a scope to check for or treat a tumor in this area, this experimental imaging method might help guide treatment.
Detroit, MichiganAges 18–75 - NCT07225621RecruitingPhase 2
Light and sound therapy for newly diagnosed glioblastoma
This trial tests a new approach that uses a light-sensitive drug and low-intensity ultrasound to make standard chemotherapy more effective for glioblastoma. If you have completed initial treatment with radiation and temozolomide without the tumor growing, you may be eligible.
Boston, MassachusettsAges 18–80 - NCT07076472RecruitingEarly Phase 1
Sound and drug therapy for recurrent glioblastoma
This trial tests a new approach that combines a drug (SONALA-001 or 5-ALA) with focused ultrasound to treat glioblastoma that has come back or is growing despite standard treatments. The drug makes tumor cells sensitive to sound waves, and the ultrasound waves are directed at the tumor using MRI guidance. This may help damage cancer cells while sparing healthy brain tissue.
Rochester, MinnesotaAges 18 years+ - NCT04400539RecruitingPhase 2
Nivolumab plus 5-ALA light treatment for pleural mesothelioma
This Phase 2 study tests whether adding nivolumab (an immunotherapy) to a one-time “light-based” treatment during a lung procedure can control malignant pleural mesothelioma that can’t be surgically removed. You may be eligible if your cancer has come back or progressed after prior platinum chemotherapy, and if your tumor is reachable for the light treatment during thoracoscopy.
LilleAges 18 years+ - NCT06039709RecruitingPhase 1
Sound wave therapy for recurrent glioblastoma
This trial tests a new treatment called sonodynamic therapy that uses sound waves and a special drug to target brain tumors that have come back. It aims to see if this approach is safe and can shrink tumors in people who are eligible for surgery.
Charlottesville, VirginiaAges 18–80 - NCT06052033Recruiting
Light therapy vs. laser for persistent cervical changes with HPV
This study compares two treatments—photodynamic therapy using a special light-activated cream and a CO2 laser—to see which works better for clearing low-grade cervical changes caused by a long-lasting high-risk HPV infection. The goal is to find a safe, effective option for women who have had this condition for over a year.
Wenzhou, ZhejiangAges 18–65 - NCT07075328RecruitingPhase 1/Phase 2
Study of OJP-001 for adult T-cell leukemia/lymphoma
This trial tests a new drug called OJP-001 for people with adult T-cell leukemia/lymphoma (ATL) that has come back or not responded to other treatments. The goal is to see if this drug can help control the disease.
Fukuoka, FukuokaAges 20–85 - NCT07111182Recruiting
Using a Dye to Guide Brain Tumor Surgery
This study tests whether a special dye called 5-ALA can help surgeons see tumor tissue more clearly during brain tumor surgery. If you are having surgery for a high-grade glioma or another brain tumor, you may be able to join and help improve surgical precision.
Chicago, IllinoisAges 18–99
What 5-ALA is being studied for
Conditions with recruiting 5-ALA studies.
Common questions
- Are there clinical trials studying 5-ALA?
- Yes. Clin2 currently lists 10 recruiting studies that include 5-ALA, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a 5-ALA trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is 5-ALA an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether 5-ALA or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.