Treatment
Kratom clinical trials
We’re tracking 5 recruiting studies that include Kratom, each written for real people, not researchers, below.
Recruiting studies
- NCT06089980Recruiting
Kratom product study for regular users
This study watches how regular kratom users react to their own kratom product. It aims to learn more about kratom's effects in real-world settings.
Baltimore, MarylandAges 21 years+ - NCT07218549RecruitingPhase 1
Study of psychoactive substances in people with past opioid use
This trial tests how safe certain psychoactive substances are and what effects they have in people who have used opioids in the past but are not currently dependent on them. It aims to gather information that could help future treatment options.
Houston, TexasAges 18–55 - NCT05846451RecruitingEarly Phase 1
Study of how kratom and oxycodone interact in healthy adults
This early study tests how kratom can change the body’s handling of oxycodone (a prescription opioid) and how safe and measurable the effects are. It may help researchers understand drug interactions, especially for people who have used kratom and opioids before.
Spokane, WashingtonAges 21–45 - NCT07469527Recruiting
Tonic for stress in healthy adults
This study tests if a tonic called Feel Free Classic Tonic can help lower stress in healthy adults. You will take the tonic, and the researchers will check your stress levels and how your body processes the drink.
Guelph, OntarioAges 21–55 - NCT05883358Recruiting
Treating kratom withdrawal with clonidine or buprenorphine
This trial studies medicines (clonidine and/or buprenorphine) to help manage kratom dependence and kratom withdrawal symptoms. You may be asked to regularly track withdrawal symptoms in diaries to help the study team monitor safety and response.
Surrey, British ColumbiaAges 20–99
What Kratom is being studied for
Conditions with recruiting Kratom studies.
Common questions
- Are there clinical trials studying Kratom?
- Yes. Clin2 currently lists 5 recruiting studies that include Kratom, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Kratom trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Kratom an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Kratom or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.