Study of how kratom and oxycodone interact in healthy adults
Part of Pain clinical trials.
This early study tests how kratom can change the body’s handling of oxycodone (a prescription opioid) and how safe and measurable the effects are. It may help researchers understand drug interactions, especially for people who have used kratom and opioids before.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be between 21 and 45 years old and in generally healthy condition
- Weigh between 130 and 250 pounds (60–115 kg) with a body mass index (BMI) between 19 and 30
- Have used kratom before and tolerated it well, and be willing to stop kratom for several weeks
- Have used opioids before and tolerated them well without addiction, and be willing to avoid opioid pain medicines during the study
- Do not take any medicines, supplements, or botanical products that could change how kratom or oxycodone work in the body (unless the study allows it)
- Live within 40 miles of Spokane and be able to attend all study visits
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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