Treatment
Opioid clinical trials
We’re tracking 443 recruiting studies that include Opioid, each written for real people, not researchers, below.
Recruiting studies
- NCT07215546Enrolling by invitation
Stopping pain after heart surgery with a special chest closure
This trial tests a new device to close the breastbone after open-heart surgery to see if it helps reduce the need for prescription pain medicine. The device is designed to hold the bone together more securely, which may lead to less pain and faster recovery.
Naples, FloridaAges 19–80 - NCT06835582Enrolling by invitation
Checking Methadone and Its Breakdown Levels
This study is checking the levels of methadone and its breakdown products in your blood. It helps make sure the medication is working safely for conditions like opioid use disorder or chronic pain.
Lemon Grove, CaliforniaAges 18–70 - NCT06699953Enrolling by invitation
EEG study of fentanyl and how it relates to drug liking
This study looks at how fentanyl affects brain waves (EEG) and whether those brain changes are linked to how much a person likes the drug. If you are having surgery with fentanyl, you may be able to join.
Palo Alto, CaliforniaAges 18 years+ - NCT06561035Enrolling by invitationPhase 3
Opioid-sparing study for ACL reconstruction
This study tests pain management options after ACL reconstruction to reduce the need for strong painkillers. It may help you recover with fewer side effects and lower risk of opioid dependence.
Memphis, TennesseeAges 14–85 - NCT06469177Enrolling by invitation
Pain management app study for joint replacement recovery
This study tests a smartphone tool to help manage pain after hip, knee, or shoulder replacement. It aims to see if using the tool improves your recovery compared to standard care.
Dartmouth, Nova ScotiaAges 19 years+ - NCT06139666Enrolling by invitationPhase 4
Liposomal bupivacaine nerve block for rotator cuff surgery
This study tests whether a long-lasting numbing medicine called liposomal bupivacaine (Exparel) works better than standard pain relief for people having rotator cuff surgery. It aims to lessen pain after surgery so you may need fewer pain pills.
Camden, New JerseyAges 18 years+ - NCT06084221Enrolling by invitation
Studying overdose review teams to improve surveillance
This study looks at how local overdose fatality review (OFR) teams work and how they can help track and prevent overdoses better. Researchers will also use anonymous administrative data to understand overdose patterns in Indiana. The goal is to make our surveillance systems stronger and save lives.
Indianapolis, IndianaAges Any age - NCT06077422Enrolling by invitationPhase 2/Phase 3
Comparing two pain blocks for heart surgery recovery
This trial compares two types of pain blocks (Exparel vs. Marcaine) given during heart surgery to see which one provides better pain relief. If you are scheduled for a heart surgery through a small or full chest incision, you may be able to join.
New Brunswick, New JerseyAges 18 years+ - NCT04499079Enrolling by invitation
ADAPT: Youth addiction prevention and treatment programs in local counties
This study tests whether a local program (called the LHS intervention) can improve addiction-related prevention and treatment for young people. You may be able to join if you live in a participating county and use a community mental health center service during the study period.
Indianapolis, IndianaAges 11–22 - NCT04356274Enrolling by invitation
Improving access to addiction and mental health care at VA clinics
This study tests an approach to help VA clinics reach more Veterans with proven treatments for addiction and mental health conditions. It focuses on clinic-level processes (not individual medications) to increase how widely evidence-based care is delivered.
Palo Alto, CaliforniaAges 18 years+ - NCT04085913Enrolling by invitationEarly Phase 1
Test shot to reduce opioid use after thyroid or parathyroid surgery
This early-phase study tests whether an injection given during thyroid or parathyroid surgery can lower how much opioid pain medicine you need afterward. It may help some people manage pain with less opioid medication.
Columbia, MissouriAges 18 years+
Common questions
- Are there clinical trials studying Opioid?
- Yes. Clin2 currently lists 443 recruiting studies that include Opioid, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Opioid trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Opioid an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Opioid or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.