Understanding Autoimmune Lymphoproliferative Syndrome
Part of Immune system & allergy clinical trials.
This research study helps doctors understand ALPS, a rare immune disorder that causes swollen lymph nodes and spleen. Participating means providing blood samples and health information so researchers can learn how the condition develops and how to better care for patients.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You or a family member have had swollen lymph nodes or enlarged spleen for more than 6 months
- You are willing to provide blood and tissue samples that may be stored for research
- You are at least 3 years old (to visit the NIH Clinical Center in person)
- You either have ALPS or are a blood relative of someone with ALPS
- If you have ALPS, blood tests show specific immune cell markers (elevated DNT cells)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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