Check biomarkers during bronchoscopy in breathing and throat pre-cancer
Part of Cancer, Digestive system, Ear, nose & throat, Lungs & breathing, Mouth & dental clinical trials.
This study looks at “biomarkers” (measurable signals in samples) taken during bronchoscopy or related procedures in people with severe airway pre-cancer or certain lung/throat cancers, and in healthy volunteers. The goal is to better understand what these biomarkers mean and how they might help with diagnosis, staging, or monitoring.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have severe or extensive airway lining dysplasia, or you don’t have dysplasia (a comparison group).
- You must be getting a bronchoscopy/panendoscopy or a related procedure for clinical reasons (not just for the study).
- If you have had cancer before: you’ve had at least 1 year since an aerodigestive cancer, and for non-small cell lung cancer it must be fully removed (stage I).
- You should not have major bleeding problems (no bleeding disorder and no unusual bleeding tendency).
- Your heart and lung health must be stable enough for bronchoscopy (for example, no recent heart attack and no serious uncontrolled heart rhythm problems).
- You should not have a recent serious lung infection (no acute bronchitis or pneumonia in the past 8 weeks, unless the doctor believes it’s from cancer) and oxygen levels should not be low before the procedure.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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