Study immune differences in HIV and HIV-negative adults
Part of Immune system & allergy, Infections clinical trials.
This research compares the immune system in the gut lining, spinal fluid, lymph nodes, and blood between people living with HIV and people not living with HIV. Results may help scientists understand how immunity works and how it differs with HIV.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be between 18 and 50 years old
- HIV testing status must match the study: HIV-negative people must test negative on specific lab tests; HIV-positive people must test positive on specific lab tests
- Be able to understand the study and give informed consent (you can have the form read to you)
- You must not have GI problems or symptoms that would usually require a scope/endo for diagnosis, or certain autoimmune conditions that could affect gut tissue
- For HIV-positive participants: no serious HIV-related infections in the last 30 days, and you must be off specific short-term treatments for at least 14 days
- You cannot have certain lab and health issues (like low platelets or clotting problems, pregnancy, untreated syphilis, neurologic red flags for spinal fluid testing, or a bleeding disorder)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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