Study of Li-Fraumeni syndrome family cancer risk
Part of Cancer, Genetic & congenital, Hormones & metabolism clinical trials.
This study collects medical and genetic information to better understand how often cancer develops in people with Li-Fraumeni syndrome and related family risks. It may help families and doctors plan earlier awareness and follow-up over a person’s lifetime.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You (or your family) have a cancer history that fits Li-Fraumeni syndrome, or you have a known TP53 gene mutation, or a close relative has it.
- Your personal or family history must be verifiable using questionnaires, interviews, medical records, and/or pathology (tissue) reports.
- You must be able to understand the study and sign consent yourself or have a legally authorized representative consent for you.
- If you are a woman who is pregnant, you can join only the data-collection part, but not the cancer screening during pregnancy.
- If you are in the cancer screening part and become pregnant, you must pause that screening until after you recover postpartum.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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