TP53 (Li-Fraumeni) family biobank and sample study
Part of Cancer, Genetic & congenital, Hormones & metabolism clinical trials.
This study collects and stores health information and biological samples from people who have a known TP53 change (Li-Fraumeni syndrome) and from close family members. The goal is to help researchers learn more about risks and future treatments for this genetic condition.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be in the study as an affected person, a TP53-negative relative, or a household member of someone with TP53 Li-Fraumeni
- You must be willing to give consent (or a parent/authorized representative must give permission for a child)
- If you are an affected participant: you have a confirmed TP53 change, or meet known Li-Fraumeni diagnosis rules based on your family history
- If you are a relative in the unaffected group: you are a biological relative of someone with a TP53 change and your own TP53 test must be negative
- If you are a household member: you have lived together in the same home for at least 6 months
- You cannot be pregnant at the time you join the study
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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