Proton radiation after lumpectomy for early breast cancer
Part of Cancer, Skin clinical trials.
This trial studies a type of radiation made with protons to treat only part of the breast after surgery (lumpectomy) for early-stage breast cancer. It may help control the cancer while aiming to reduce radiation to surrounding tissues.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be female and age 50 or older.
- Your breast cancer diagnosis must be proven by pathology as invasive ductal cancer or DCIS (lobular cancer is not allowed).
- The tumor must be early stage (Stage 0, I, or II), and if Stage II the tumor must be 3 cm or smaller.
- Your surgery must be a lumpectomy with clear margins (negative) by at least 0.2 cm, and you must start treatment within set timelines after surgery/chemo.
- Your cancer must be ER positive, and for invasive cancer the HER2 test must have been done (either positive or negative is allowed).
- You must be able to use the trial’s treatment planning setup, including having clips/markers placed if needed for daily image guidance.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study compares two types of proton radiation after lumpectomy for early breast cancer. It tests whether a shorter, stronger course (ultra-hypofractionated) works as well as a slightly longer moderate course.
This trial tests a short, highly targeted radiation plan given in five sessions after lumpectomy for early-stage breast cancer. It may help treat the remaining breast area while aiming to limit exposure to healthy tissue.
This trial tests a shorter, more intense course of daily radiation therapy (called ultra hypo-fractionation) given after lumpectomy for early-stage breast cancer. The goal is to reduce the number of treatment visits while keeping the same high level of effectiveness and safety.
This trial studies whether a specific radiation approach after lumpectomy can be helpful for certain people with early breast cancer that did not spread to lymph nodes at diagnosis. It focuses on people who finish neoadjuvant (before-surgery) treatment and reach a full response on final pathology.
This study compares two different ways of giving radiation to the breast after lumpectomy for early-stage breast cancer. It may help determine which approach controls the cancer well while reducing radiation to surrounding healthy tissue.
This trial studies a type of radiation made with proton beams given after mastectomy and implant reconstruction to lower breast cancer coming back. It’s for people who need additional (adjuvant) radiation and have not had prior radiation to the chest or breast.
Hear when a new Breast cancer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.