PET scans and lymph node checks for HIV immune rebound
Part of Immune system & allergy clinical trials.
This study looks at people with HIV who either have not started HIV medicines yet or who recently started/changed them and may develop immune rebound (IRIS). It uses blood tests and optional PET/CT scans and lymph node biopsies to understand what’s happening in the body and to guide care.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are at least 18 years old and have a confirmed HIV diagnosis
- You must live within about 100 miles of NIH in Bethesda and plan to stay nearby for 48 weeks
- You must have recent lab results showing very low immune cells (CD4) or be suspected of IRIS after starting/changing HIV treatment
- You’re willing to have blood draws, possible apheresis, and an optional PET/CT scan and lymph node biopsy
- You’re willing to store blood/tissue samples for future research and do genetic testing
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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