Clin2
NCT02414178Possibly a fitEnrolling by invitation

Tau PET brain scan for inherited Alzheimer’s disease

Alzheimer Disease

Part of Brain & nervous system, Mental health clinical trials.

This study uses a special brain scan to measure “tau” buildup in people with an inherited form of Alzheimer’s. It may help researchers better understand disease changes and evaluate whether the scan can track them over time.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
130 people
Ages
18 years and older
Study type
Observational

Who can take part

  • You must already be enrolled in the DIAN Performance Site or DIAN Extended Registry (DIAN).
  • You are age 18 or older.
  • You are either cognitively normal or have mild dementia, based on a clinical check.
  • You can undergo scan testing, including MRI or CT, plus a PET scan with an injected radioactive tracer.
  • If you are able to become pregnant (pre-menopausal), you must have a negative urine pregnancy test within 24 hours of the injection.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT02414347Recruiting
Tau PET scan study for Alzheimer’s disease

This study uses a PET brain scan with a small injected tracer to look for “tau” protein changes linked to Alzheimer’s disease. It may help researchers better understand how tau appears in people who are cognitively normal or have mild dementia.

St Louis, Missouri
NCT04104659Enrolling by invitation
Tau PET scan study to map brain changes in Alzheimer’s

This study tests a PET scan “tracer” medicine called [18F]MK-6240 to see how tau protein changes show up in the brain. It may help researchers measure disease-related brain changes in people with normal thinking or mild dementia.

St Louis, Missouri
NCT06723015Enrolling by invitation· Phase 2
Tau PET in anti-amyloid therapy for Alzheimer's

This study uses brain scans to see how anti-amyloid treatments affect tau protein buildup in people with early Alzheimer's. If you have mild cognitive impairment or mild Alzheimer's, you may be eligible to help understand how these treatments work.

Rochester, Minnesota
NCT03809351Recruiting· Phase 1
Brain tau scan add-on for people in the UAB Alzheimer studies

This trial tests an added brain imaging scan that looks for “tau” protein in people already enrolled in the UAB Alzheimer research studies. Results may help researchers better understand Alzheimer’s disease and improve future diagnosis.

Birmingham, Alabama
NCT05456503Recruiting· Phase 3
PET scan study of tau buildup in memory and brain disorders

This Phase 3 study uses a PET/CT scan to measure whether a brain protein called tau (and related disease patterns) builds up in different dementia conditions. The goal is to better match which disorders have which brain changes and how they progress.

Philadelphia, Pennsylvania
NCT05582200Recruiting
PET brain scan to study inflammation cells in Alzheimer’s

This study uses a special PET brain scan to look at two types of brain immune cells in people with Alzheimer’s. It may help researchers better understand Alzheimer’s and how these cells change over time.

Houston, Texas

Hear when a new Alzheimer Disease trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.