PET scan study of tau buildup in memory and brain disorders
Treatments studied
Part of Brain & nervous system, Hormones & metabolism, Mental health clinical trials.
This Phase 3 study uses a PET/CT scan to measure whether a brain protein called tau (and related disease patterns) builds up in different dementia conditions. The goal is to better match which disorders have which brain changes and how they progress.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 18 or older and currently enrolled in the UNICORN study
- A trained clinician has diagnosed you with one of the study conditions (normal aging, non-amnestic Alzheimer’s, or a frontotemporal dementia type, or a specific genetic mutation)
- Your mood is not significantly depressed (or a clinician says you are not clinically depressed)
- You can safely have a PET/CT scan (including MRI review) with no major safety or imaging issues
- If required for your group, you have a study partner and a legally authorized representative (LAR) who can join visits
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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