Screening for inner-ear tumors in people with Von Hippel-Lindau
Part of Brain & nervous system, Genetic & congenital, Heart & circulation clinical trials.
This trial focuses on checking whether a specific inner-ear tumor (called an endolymphatic sac tumor) can be found earlier in people with Von Hippel-Lindau (vHL) disease. It may help doctors detect problems sooner so you can discuss treatment options earlier, if needed.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a diagnosis of Von Hippel-Lindau (vHL), either by genetic testing or by clinical signs (and possibly family history)
- You must be at least 15 years old
- You had an ear hearing test (like an audiogram) within the last 12 months
- You had an MRI scan of your brain that includes the inner ear within 12 months
- Your hearing test and MRI should be done within 12 months of each other
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests delivering gene therapy into the inner-ear hearing balance nerve cells during surgery for vestibular schwannoma. It may help by improving how the inner ear functions after tumor removal, but you must meet several specific surgery and safety requirements.
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