First test of an implant device to prevent sleep apnea pauses
Part of Brain & nervous system, Lungs & breathing clinical trials.
This trial is testing whether a new implanted device is safe and feasible for people with moderate to severe obstructive sleep apnea. It may help if you cannot tolerate CPAP (a common breathing device) and your apnea is caused by airflow blockage at the back of the tongue area.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be between 21 and 70 years old
- Have moderate to severe obstructive sleep apnea (about 15–50 breathing pauses per hour)
- Have tried CPAP but couldn’t tolerate it (using it less than 2 hours per night for at least 5 nights/week)
- Be able to sign consent and understand the study plan and risks
- Have apnea caused by blockage at the base of the tongue—not a different type like central apnea
- Be able to have an implanted device placed and have no metal or other reasons MRI/surgery would be risky
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a new proactive therapy for people recently diagnosed with moderate or severe sleep apnea. It aims to see how well patients stick with the treatment outside of a sleep lab.
This trial tests a new nerve-stimulation therapy called Neuromod to treat moderate-to-severe sleep apnea in people who do not have access to other treatments. If you qualify, you would be part of a study to see if this implant helps improve your breathing during sleep.
This study is comparing two alternative treatments for moderate to severe sleep apnea in people who cannot or will not use a CPAP machine. The treatments are a custom-fitted dental device and a nerve stimulation implant, and the study will see how well they work.
This study tests whether adding a special mouthpiece (mandibular advancement device) can help people whose sleep apnea wasn't fully treated by a nerve stimulator implant. You would use the mouthpiece at night and take home sleep tests to see if your breathing improves.
This study looks at a new way to use digital dental scans to fit a mouthpiece that treats obstructive sleep apnea. If you use this mouthpiece, the study may help make fitting more comfortable and accurate.
This trial tests a nerve-stimulation implant for sleep apnea when other treatments haven't worked. It may help if you have moderate to severe apnea, a BMI under 32, and have tried CPAP and a mouth device without success.
Hear when a new Obstructive Sleep Apnea trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.