Red yeast rice plus low-dose statin versus statin alone
Part of Heart & circulation, Hormones & metabolism clinical trials.
This Phase 3 study compares whether taking red yeast rice plus a low-dose statin works better and is as safe as taking a standard statin alone. It aims to improve cholesterol (especially LDL) and reduce cardiovascular risk in people with mild, confirmed artery disease.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have mild artery disease shown by scans (coronary, carotid, and/or leg arteries) and your LDL “bad cholesterol” is above 70 mg/dL.
- If you can get pregnant, you must be postmenopausal, surgically unable to become pregnant, or use two reliable contraception methods (with a negative pregnancy test).
- You must agree to sign consent and follow study visits, blood tests, and the treatment plan.
- Before screening, you must not have taken statins or red yeast rice products within the past 4 weeks.
- You must not have certain serious past heart/brain/vascular events (like heart attack, stroke, unstable chest pain) or have certain planned procedures during the study.
- You must not have significant liver or kidney problems, uncontrolled blood pressure, certain stomach ulcers, or specific hormone/gallbladder/pancreas conditions.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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