Clin2
NCT02914951Possibly a fitEnrolling by invitation

Therapy to reduce irritability in children with autism

AutismIntellectual Disability

Part of Brain & nervous system, Mental health clinical trials.

This trial studies whether cognitive-behavioral therapy (a structured talk therapy) can reduce irritability and anger outbursts in children with autism. It may help improve day-to-day behavior by teaching coping skills and reducing problem reactions.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
6 people
Ages
8 years to 16 years
Study type
Interventional

Who can take part

  • Your child has been diagnosed with autism spectrum disorder (DSM-5).
  • Your child has disruptive irritability—like anger outbursts.
  • Your child’s IQ is between 55 and 85.
  • Your child scores high enough on an irritability rating (ABC Irritability score 15 or above).
  • Your child is not starting new medicines, or is on a stable medication regimen.
  • Your child can complete all study check-ins and brain scan (fMRI) procedures.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07245160Not yet recruiting
Cognitive behavioral therapy for anxiety in autistic teens

This study tests a type of talk therapy called cognitive behavioral therapy (CBT) to help reduce anxiety in teenagers with autism and intellectual disability. It may help your child learn new ways to cope with anxiety.

London, Ontario
NCT06974838Recruiting
Theta burst stimulation for emotion regulation in autism

This trial tests a type of brain stimulation called theta burst stimulation to see if it helps people with autism who have limited verbal skills or intellectual disability manage their emotions better. It may offer a new way to support emotional well-being.

Taoyuan
NCT06214065Recruiting
Brain stimulation for social thinking in autism

This trial tests whether mild brain stimulation (TMS) over the temporoparietal junction can improve a social thinking skill called 'mentalizing' in adults with autism. You would have MRI scans, cognitive tasks, and several TMS sessions.

Hartford, Connecticut
NCT03202303Recruiting· Phase 2
CBDV treatment study for children with autism irritability

This Phase 2 study tests CBDV, a form of cannabis-based medicine, compared with placebo (dummy medicine) in children with autism who have significant irritability and social challenges. It aims to see whether CBDV can improve behavior and overall symptom severity safely over the study period.

New York, New York
NCT05928247Recruiting
Behavior program for frequent challenging behaviors in children

This trial tests a structured (manualized) assessment and treatment approach for children who have very frequent challenging behaviors despite prior help. It aims to reduce these behaviors and improve daily functioning by targeting what keeps the behavior going.

Somerset, New Jersey
NCT02531893Recruiting
Therapy for youth with severe, frequent irritability

This study tests whether two structured therapies can reduce severe irritability and angry reactions in children and teens. It focuses on youth who have had long-lasting, frequent outbursts and trouble responding to negative emotions.

Bethesda, Maryland

Hear when a new Autism trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.