Study for severe mitral valve disease when surgery isn’t an option
Part of Heart & circulation clinical trials.
This trial focuses on people with severe mitral valve narrowing or leaking who still have symptoms even after the best usual medications. It may help find better care and measure health outcomes when surgery is judged too risky or not suitable.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are over 18 years old.
- You have severe mitral valve narrowing (stenosis) or leaking (regurgitation).
- You still have symptoms despite taking the best medical treatment available.
- A hospital team (“heart team”) decides you are not eligible for surgery.
- You were told about the study and did not object to using your medical data.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study is following people with heart valve disease (leaky or narrowed valves) to understand how the disease changes over time and what problems it may cause. It does not test a new treatment, but helps doctors learn more about valve disease progression.
This study keeps a registry of adults who have a mitral valve problem and are being evaluated for a catheter-based mitral valve replacement. It helps doctors understand what treatments are used and how patients do.
This study is a registry (a way to track real-world outcomes) for people with mitral valve disease who receive a mitral valve procedure. It helps doctors understand how well these procedures work and what complications happen in patients like you.
This study tests a new device called the MRace implant that is designed to repair a leaky mitral valve without open-heart surgery. It may help people with severe leakage who are at high risk for traditional surgery.
This trial tests a new device to fix a leaky mitral valve in people with moderate to severe leakage who are too high-risk for open-heart surgery. It aims to improve heart function and symptoms.
This trial studies severe secondary mitral valve leaking and uses heart imaging to predict how well the heart and symptoms improve after a less-invasive valve procedure. It may help doctors better forecast who benefits most from this repair.
Hear when a new Mitral Valve Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.