Early study of a new implant for leaking heart valve
Part of Heart & circulation clinical trials.
This study tests a new device called the MRace implant that is designed to repair a leaky mitral valve without open-heart surgery. It may help people with severe leakage who are at high risk for traditional surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You must have severe mitral valve leakage (grade 3+ or higher), which means the valve does not close properly and blood flows backward.
- You must have symptoms of heart failure that limit your daily activities (NYHA class III or IV).
- Your risk for traditional heart surgery must be high but not too high (STS score less than 10%).
- You must be able to attend follow-up visits and provide informed consent.
- You must not have certain other heart conditions, recent surgeries, or medical issues that could interfere with the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new device called MRace that may fix a leaky mitral valve without open-heart surgery. It's for people whose valve leaks severely and who can't have standard surgery due to other health issues.
This study looks at how safe and effective a specific catheter procedure is for people with moderate-to-severe mitral valve leakage. It may help those who are considered high risk for traditional open-heart surgery.
This study tests a new device called MRace that is placed through a vein in the leg to fix a leaky mitral valve in people whose valve shape is not suitable for the usual repair. It is for patients with heart failure and moderate-to-severe regurgitation who are still able to have surgery but are considered high risk.
This study tests a new device called MRace that is placed through a vein in the leg to fix a leaky mitral valve (the valve between the upper and lower left heart chambers). It is for people who have significant leakage and whose heart anatomy does not allow the usual clip repair. The goal is to see if the MRace can safely and effectively reduce the leak and improve symptoms.
This study tests a new device, MRace, for people with severe functional mitral regurgitation, a condition where the heart's mitral valve doesn't close fully, causing blood to leak backward. The trial is for patients who have unusual heart structures that make the standard clip procedure difficult. The goal is to see if MRace can safely and effectively fix the leak and improve symptoms.
This trial tests a new device called the Capstan system to fix a leaky mitral valve (mitral regurgitation) without open-heart surgery. It may help people whose valve leak is moderate to severe and still have symptoms despite medicines.
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