Early study of a new implant for leaking heart valve
Part of Heart & circulation clinical trials.
This study tests a new device called the MRace implant that is designed to repair a leaky mitral valve without open-heart surgery. It may help people with severe leakage who are at high risk for traditional surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You must have severe mitral valve leakage (grade 3+ or higher), which means the valve does not close properly and blood flows backward.
- You must have symptoms of heart failure that limit your daily activities (NYHA class III or IV).
- Your risk for traditional heart surgery must be high but not too high (STS score less than 10%).
- You must be able to attend follow-up visits and provide informed consent.
- You must not have certain other heart conditions, recent surgeries, or medical issues that could interfere with the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new device called MRace that may fix a leaky mitral valve without open-heart surgery. It's for people whose valve leaks severely and who can't have standard surgery due to other health issues.
This trial tests a new device to fix a leaky mitral valve in people with moderate to severe leakage who are too high-risk for open-heart surgery. It aims to improve heart function and symptoms.
This trial tests a new device, called MRace, that is placed with a thin tube into the heart to fix a leaky mitral valve. It's for people whose valve is too complex for the usual clip repair, and who are too high-risk for open-heart surgery.
This study tests a new device called MRace for people with a leaking mitral valve (functional mitral regurgitation) whose heart structure makes standard repair difficult. The device is placed through a vein in the leg to fix the leak without open-heart surgery.
This study tests a new device (MRace) for people with a leaky mitral valve whose anatomy is too complex for the standard clip treatment. The device is placed through a vein in the leg to help the valve close better, which may reduce symptoms and improve quality of life.
This trial tests a new device called the Capstan system to fix a leaky mitral valve (mitral regurgitation) without open-heart surgery. It may help people whose valve leak is moderate to severe and still have symptoms despite medicines.
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