Fluoride scan–guided treatment for painful knee arthritis
Treatments studied
Part of Bones, joints & muscles clinical trials.
This trial studies a targeted treatment using a fluoride-related injection to help reduce pain from knee osteoarthritis. To join, you need a painful osteoarthritis knee and a specific bone-scan finding (SUV above 10) on an imaging test.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have painful knee osteoarthritis (wear-and-tear joint arthritis).
- Your knee passes an 18F sodium fluoride bone scan showing SUV greater than 10.
- You are willing to join and sign an informed consent form.
- You have NOT had knee joint replacement surgery.
- Your knee pain is not from infection, inflammatory arthritis, gout, or a recent injury/fracture.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a treatment that uses heat to calm the nerves around the knee, which may reduce pain for people with advanced knee arthritis who haven't gotten relief from other treatments.
This study tests how well and how safely a knee treatment works for adults with painful knee osteoarthritis seen on X-ray. You might join if you need meaningful pain relief and help with daily function, and can complete required scans and study instructions.
This study tests how well different pain medicines work for knee osteoarthritis and looks at brain patterns to understand why some people get more relief. It may help you find a treatment that works best for you.
This study uses brain scans to understand different types of knee pain in women with knee osteoarthritis.
This study tests a low-dose radiation treatment for knee osteoarthritis pain. If you have moderate arthritis pain and are a Mayo Clinic patient in Rochester, you may be able to join.
This study tests a new antibody drug (FB1003) for people with knee osteoarthritis pain. It will check if the drug is safe and helps reduce pain. You may be eligible if you have moderate to severe knee pain and are willing to temporarily stop your usual pain medications.
Hear when a new Treatment Outcome trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.