Pain medicine study for knee osteoarthritis
Treatments studied
Part of Bones, joints & muscles clinical trials.
This study tests how well different pain medicines work for knee osteoarthritis and looks at brain patterns to understand why some people get more relief. It may help you find a treatment that works best for you.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 40 years or older.
- You have knee pain most days for the past month.
- Your average knee pain last week was at least 4 out of 10.
- You can walk with or without a cane but not a walker or wheelchair.
- You are not currently taking certain pain medicines like high-dose opioids, strong antidepressants, or cannabis for knee pain.
- You do not have other types of arthritis or serious health conditions like uncontrolled heart or liver disease.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at how knee pain from osteoarthritis affects your daily life and health. You'll use a topical anti-inflammatory gel and answer questions by text or email for two months.
This study tests whether taking the pain medication duloxetine before and after knee replacement surgery can reduce the need for opioid painkillers. It may help patients manage pain with fewer side effects from strong narcotics.
This study tests a personalized approach to managing knee osteoarthritis pain by engaging the brain's natural pain-control systems. It aims to find the best way to reduce pain for each person, potentially offering a new option for those with long-term knee pain.
This study tests whether a new medicine (ALT001) can safely reduce knee pain from osteoarthritis. If you join, you would stop your current pain medicines and take the study drug or a placebo for a set time, while being closely monitored.
This study looks at how walking patterns relate to knee pain from osteoarthritis. It aims to understand individual differences to improve future treatments.
This trial tests if learning about chronic pain can help people with knee osteoarthritis feel better. You'll join a program that teaches you about pain and how to manage it.
Hear when a new Knee Osteoarthritis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.