Treatment
Celecoxib clinical trials
We’re tracking 32 recruiting studies that include Celecoxib, each written for real people, not researchers, below.
Recruiting studies
- NCT03926338RecruitingPhase 2
Before-surgery immunotherapy for MSI-H or dMMR colon cancer
This trial studies a treatment given before surgery using toripalimab, with or without celecoxib, for colon or rectal cancer that has MSI-H or dMMR tumor features. It aims to shrink or control the cancer before the operation and compare whether adding celecoxib helps.
Guangzhou, GuangdongAges 18–75 - NCT01344200RecruitingPhase 2
Celecoxib drug study in children on leukemia treatment
This trial studies how celecoxib moves through a child’s body and how much reaches the fluid around the brain and spinal cord. It’s for children (age 2–12) who are in the maintenance phase of certain blood cancers, to better understand dosing and safety.
Ottawa, OntarioAges 2–12 - NCT06545526RecruitingPhase 3
Celecoxib and metformin for familial adenomatous polyposis
This trial tests whether a combination of two drugs, celecoxib and metformin, can prevent the growth of polyps in the colon or duodenum (the first part of the small intestine) in people with familial adenomatous polyposis (FAP). FAP is a condition that causes many polyps to form, raising the risk of cancer. If you have FAP, are between 20 and 55, and have at least 5 polyps that are 2mm or larger, this study may be for you.
SeoulAges 20–55 - NCT06722534Recruiting
Celecoxib to prevent polyps from growing in Peutz-Jeghers Syndrome
This trial is testing if the medication celecoxib can stop or slow the growth of polyps in people with Peutz-Jeghers Syndrome (PJS). It may help reduce the need for surgery and lower the risk of complications.
Xi'an, ShaanxiAges 8 years+ - NCT06863636RecruitingPhase 3
Combination painkiller vs celecoxib for osteoarthritis flare-ups
This study tests whether a combination of two pain relievers (celecoxib and acetaminophen) works better than celecoxib alone for sudden, severe osteoarthritis pain in the knee or hip.
Mexico CityAges 40 years+ - NCT06505187RecruitingPhase 2
Celecoxib for Pain After Parotid Gland Surgery
This trial is testing whether the pain reliever celecoxib (Celebrex) can help control pain after a specific type of salivary gland surgery called superficial parotidectomy. If you're having this surgery, you may be able to join and take celecoxib for pain rather than other common pain medicines.
Madison, WisconsinAges 18 years+ - NCT07351968RecruitingPhase 1
Study of HRS-2129 for knee osteoarthritis pain
This trial tests an investigational drug, HRS-2129, for people with knee osteoarthritis who have moderate to severe pain. It aims to see if the drug is safe and effective at reducing pain.
Nanjing, JiangsuAges 18–80 - NCT07494565RecruitingPhase 2
Celecoxib plus standard chemo for CD5+ DLBCL
This trial tests whether adding celecoxib (an anti-inflammatory drug) to the standard R-CHOP chemotherapy regimen can improve outcomes for people with a specific, hard-to-treat type of diffuse large B-cell lymphoma (DLBCL) that is CD5-positive. It's for people who are newly diagnosed and have advanced disease.
Guangzhou, GuangdongAges 18–80 - NCT05434065RecruitingPhase 2
Celecoxib for brain bleeding after onset
This Phase 2 trial tests whether celecoxib (an anti-inflammatory medicine) can improve outcomes after an intracerebral hemorrhage (a type of stroke caused by bleeding in the brain). It also studies how the medicine may help the body recover. You would need to start treatment quickly after symptoms begin and meet several safety and bleeding-control requirements.
TaipeiAges 20–80 - NCT05637086RecruitingPhase 2
Test pentoxifylline plus celecoxib for grand mal epilepsy on phenytoin
This Phase 2 study tests whether adding two medicines—pentoxifylline and celecoxib—to current phenytoin treatment is safe and may help people with grand mal (generalized) epilepsy. It focuses mainly on safety while you stay on a single epilepsy medicine.
Al MansurahAges 18–75 - NCT05731726RecruitingPhase 2
New treatment before surgery for locally advanced rectal cancer
This trial tests whether giving serplulimab (an immune medicine) plus CAPEOX chemotherapy and celecoxib before surgery can shrink locally advanced rectal cancer and improve outcomes. It may help by increasing immune attack on the tumor while chemotherapy helps reduce the cancer before the operation.
Hangzhou, ZhejiangAges 18–75 - NCT06903858RecruitingPhase 2
Toripalimab plus celecoxib for dMMR/MSI-H colorectal cancer
This trial tests whether combining toripalimab (an immunotherapy) with celecoxib (an anti-inflammatory drug) can shrink locally advanced colorectal tumors that have specific genetic features (dMMR or MSI-H). It aims to help people who haven't had any prior treatment for their colorectal cancer.
Guangzhou, GuangdongAges 18 years+ - NCT06997068RecruitingPhase 2
Drug combination for returning head and neck cancer
This trial tests a combination of three drugs—methotrexate, erlotinib, and celecoxib—for people whose head and neck cancer has come back or spread. It is designed for patients in the rural Midwest who have already had or chosen not to have standard first treatment.
Rochester, MinnesotaAges 18 years+ - NCT07104266RecruitingPhase 2
Celecoxib for early triple-negative breast cancer
This research study tests whether adding a drug called celecoxib (an anti-inflammatory pill) can help treat early-stage triple-negative breast cancer after surgery, before or during radiation therapy. You may be eligible if your cancer was removed cleanly and you do not have other health issues like stomach ulcers, kidney problems, or a history of allergic reactions to certain pain relievers.
Sherbrooke, QuebecAges 18 years+ - NCT07174570RecruitingPhase 2
Celecoxib with immunotherapy for advanced liver cancer
This trial tests a combination of two immunotherapy drugs (durvalumab and tremelimumab) plus a pain reliever (celecoxib) for people with advanced liver cancer that cannot be removed by surgery. The goal is to see if this three-drug combination works better than standard treatments.
Atlanta, GeorgiaAges 18 years+ - NCT07246278RecruitingPhase 1/Phase 2
Celecoxib for Parkinson's: A new way to treat symptoms
This trial tests if adding celecoxib, an anti-inflammatory drug, to standard Parkinson's treatment can help improve symptoms. If you have Parkinson's disease and are at least 18, this study might be an option for you.
TantaAges 50–80 - NCT03825809RecruitingPhase 2/Phase 3
Non-narcotic pain medicine after labral shoulder surgery
This trial studies whether a non-narcotic pain plan after labral (shoulder) surgery can control pain as well as or better than usual treatment. It may help patients avoid opioid (narcotic) pain medicines after surgery.
Detroit, MichiganAges 18 years+ - NCT04469530RecruitingPhase 2
Sirolimus plus low-dose chemotherapy for high-risk childhood tumors
This Phase 2 study tests whether sirolimus combined with low-dose (“metronomic”) chemotherapy can help children and young adults with certain high-risk solid tumors stay in remission or reduce recurrence risk. It is designed for people whose cancer has responded well to initial treatment, with only minimal or no visible disease on scans.
Atlanta, GeorgiaAges 1–30 - NCT07543796RecruitingPhase 2
Pain Relief After Hip Replacement Surgery
This study tests whether a new pain medication called TRD205 works well and is safe for people recovering from hip replacement surgery. If it works, it could offer better pain control after your operation.
Guangzhou, GuangdongAges 18–80 - NCT07150949RecruitingPhase 2
Comparing two radiation schedules with chemotherapy and immunotherapy for rectal cancer
This study tests two different radiation regimens (long-course vs. short-course) combined with chemotherapy (CAPOX), an immunotherapy drug (PD-1 antibody), and a COX-2 inhibitor for people with MSS locally advanced rectal cancer. The goal is to see which approach works better in shrinking the tumor before surgery.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06231758RecruitingPhase 3
Metformin for knee osteoarthritis: a phase 3 trial
This study tests whether metformin, a common diabetes medication, can help reduce pain and improve knee function in people with knee osteoarthritis. It may offer a new treatment option for those with moderate knee OA.
Damietta, New DamiettaAges 30–60 - NCT03026140RecruitingPhase 2
Tested immune therapy before surgery for early colon cancer
This Phase 2 trial tests immune “checkpoint” medicines (and combinations) given before colon surgery to see if they can better control early colon cancer. It is aimed at people with non-metastatic colon cancer and certain tumor markers.
AmsterdamAges 18 years+ - NCT03498326RecruitingPhase 2
Gemcitabine plus celecoxib after pancreatic surgery
This trial tests whether adding celecoxib to gemcitabine chemotherapy after complete (R0) pancreatic tumor removal can lower the chance the cancer comes back. It may help people who have had successful surgery but still need anti-cancer treatment.
Hangzhou, ZhejiangAges 18–90 - NCT05343013RecruitingPhase 2
TAS-102 with or without celecoxib for leftover colon cancer DNA
This Phase 2 study tests TAS-102, with or without celecoxib, to treat “minimal residual disease” (tiny traces of colon cancer) found in a blood test after standard chemotherapy. The goal is to reduce the chance that colon cancer returns after treatment.
Houston, TexasAges 18 years+
What Celecoxib is being studied for
Conditions with recruiting Celecoxib studies.
Common questions
- Are there clinical trials studying Celecoxib?
- Yes. Clin2 currently lists 32 recruiting studies that include Celecoxib, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Celecoxib trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Celecoxib an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Celecoxib or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.