Clin2
NCT03011814Possibly a fitRecruiting

Durvalumab plus lenalidomide for relapsed T-cell lymphoma

Folliculotropic Mycosis FungoidesRecurrent Cutaneous T-Cell Non-Hodgkin LymphomaRecurrent Mycosis FungoidesRefractory Cutaneous T-Cell Non-Hodgkin LymphomaRefractory Mycosis FungoidesRefractory Peripheral T-Cell Lymphoma, Not Otherwise SpecifiedSezary SyndromeRecurrent Mature T- and NK-Cell Non-Hodgkin Lymphoma

Treatments studied

Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.

This study tests a combination of two drugs—durvalumab (an immunotherapy) and lenalidomide (a targeted therapy)—to see if they are safe and effective for people with T-cell lymphoma that has come back or not responded to treatment. It aims to harness your immune system to fight the cancer while also attacking the cancer cells directly.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
78 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must have a type of lymphoma called cutaneous T-cell lymphoma (CTCL) or peripheral T-cell lymphoma (PTCL).
  • You must have tried at least two prior treatments for your lymphoma, and it must have come back or not responded.
  • You need to be in relatively good health, with adequate blood counts, kidney and liver function.
  • Women who can have children must use two reliable forms of birth control, and men must use effective contraception, from the start of the study until 90 days after the last dose.
  • You cannot have had a stem cell transplant, major surgery within 28 days, or certain other medical conditions.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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