Lactated ringer's solution to prevent post-ERCP pancreatitis
Treatments studied
Part of Digestive system clinical trials.
This study tests whether giving a specific IV fluid (lactated Ringer's solution) before and after an ERCP can reduce the chance of getting pancreatitis (a painful pancreas inflammation) after the procedure. It aims to prevent this complication in people who are already at higher risk.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 to 74 years old.
- You must be having a planned ERCP (a scope test of your bile and pancreas tubes) and be at higher-than-usual risk for the procedure causing pancreatitis (pancreas swelling).
- You can qualify if you have any one major risk factor (like previous post-ERCP pancreatitis) OR at least two minor risk factors (like being under 50 or having had repeated pancreatitis).
- You must NOT have certain health conditions — such as current acute pancreatitis, chronic pancreatitis, cholangitis (bile duct infection), or problems with heart, kidney, or fluid balance.
- You must NOT be pregnant, and you must be able to give informed consent.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests if giving fluids before an ERCP procedure can lower the risk of developing pancreatitis (inflammation of the pancreas). It may help people who have not had this procedure before.
This Phase 3 study tests whether putting an anti-inflammatory medicine into the rectum (indomethacin) plus taking an immune-suppressing pill (tacrolimus) works better than using the two medicines in a different combination to prevent pancreatitis after an ERCP procedure. If you qualify, you may be assigned to one of the treatment options to lower your risk of post-ERCP pancreas inflammation.
This study tests whether a rectal dose of indomethacin (an anti-inflammatory drug) can help prevent complications after an ERCP. It is for people who have already had a sphincterotomy and are having another ERCP to treat bile duct issues.
This trial tests whether giving extra IV fluids before, during, and after an ERCP procedure can help prevent a common complication called post-ERCP pancreatitis (inflammation of the pancreas). If you are scheduled for an ERCP, you may be eligible to participate.
This study tests whether giving IV (through-the-vein) fluids during/around an ERCP procedure can lower the risk of painful pancreas inflammation afterward. It may help patients by reducing a common complication after ERCP.
This study tests whether giving lidocaine during an ERCP procedure can lower the risk of a painful complication called pancreatitis. If you’re scheduled for ERCP with a “never-treated” opening, this trial may see if lidocaine helps you avoid post-procedure pancreas inflammation.
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