Heart valve replacement using a catheter for leaking mitral valve
Part of Blood & lymphatic, Cancer, Digestive system, Heart & circulation, Immune system & allergy clinical trials.
This trial studies a catheter-based procedure to replace the mitral valve in people with severe (or specific moderate) mitral valve leakage that causes symptoms. It may help by reducing leaking and related symptoms when standard surgery or less invasive fixes aren’t suitable for you.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have symptomatic moderate-to-severe or severe mitral valve leakage (or moderate leakage plus mitral narrowing with specific calcification).
- Your heart team at the study site agrees you are not a good candidate for approved catheter repair or traditional mitral valve surgery.
- You can and agree to return for all required follow-up visits after the procedure.
- You are able to give informed consent based on your local age rules.
- Your heart valve and heart structure are suitable for this specific catheter device (Medtronic Intrepid TMVR, through the groin).
- Your health is stable enough for the study (not expected to live <24 months; no need for urgent/emergency surgery).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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