Estradiol patch study for hormone signaling in PCOS
Treatments studied
Part of Cancer, Hormones & metabolism, Women’s health & pregnancy clinical trials.
This early-stage study tests whether adding an estrogen skin patch (estradiol) can change how your body releases key reproductive hormones in adults with PCOS. It may help researchers better understand PCOS-related hormone control and signaling.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a woman, age 18 to 30, and at least 4 years past your first period
- If you have PCOS: you have irregular periods (fewer than 9 per year) plus higher-than-normal “male-type” hormones such as excess hair growth or higher free testosterone
- If you are a control volunteer: your periods are regular (every 26–35 days) and you do not have excess hair growth and your free testosterone is normal
- You are generally healthy for the study, except for PCOS (and thyroid issues must be well treated)
- You must agree to not get pregnant during the study and use reliable non-hormonal birth control
- You likely do NOT have other hormone or endocrine disorders that can look like PCOS (they will screen with blood tests and history)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This early study looks at how certain “male-type” hormones and brain signals (measured through hormone patterns during the day and night) work in adolescent girls with high androgen levels. It may help researchers better understand causes like PCOS and related hormone timing differences.
This study looks at hormone levels and metabolism in people who may have polycystic ovary syndrome (PCOS). It aims to better understand why PCOS happens, which could help improve future diagnosis and treatment.
This trial aims to improve diagnosis and treatment for women with PCOS. It studies women of Indian origin aged 18-45 to find better ways to identify and manage the condition.
This study looks at how weight changes affect hormone levels and insulin resistance in women with PCOS. It may help understand if weight cycling is harmful or helpful.
This study follows women with PCOS (a hormone-related condition that can affect periods and other body functions). It’s for women who are not pregnant, helping researchers better understand PCOS over time.
This trial studies whether a team of doctors from different specialties can better diagnose and treat PCOS. If you have PCOS and are looking for a more comprehensive approach, this study may be a good fit.
Hear when a new Polycystic Ovary Syndrome trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.