Pain biomarker study for headache or back nerve pain
Part of Brain & nervous system, Injuries & trauma clinical trials.
This study looks at measurable “pain signals” (biomarkers) in people with certain headache disorders or lumbar nerve pain, and compares them with healthy people. It may help researchers better understand what drives pain and how it can be detected.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older
- You have one of these: migraine/tension/cluster or related headache syndromes, or a doctor-diagnosed lumbar radiculopathy, or you are a healthy control with no severe headache or back/nerve pain in the past 3 months
- You can sign a HIPAA form allowing the study team to access your prior records and imaging
- You do not have a history of major heart/brain blood-vessel problems, brain tumors, or epilepsy
- You are not pregnant or breastfeeding, and you don’t currently smoke or use nicotine daily
- You are able and willing to give informed consent, and you don’t have active substance use that would interfere with study visits
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at people with certain severe headache disorders (cluster-type headaches or SUNCT/SUNA) or trigeminal neuralgia (sharp facial nerve pain). Researchers want to better understand these conditions and see how study testing/record review may help care.
This study examines how sensitive the skin and tissues around the head are in people with migraines or tension headaches. Researchers will perform gentle touch and pressure tests to understand pain patterns, which may help improve headache treatment in the future.
This study follows kids who have a specific type of chronic pain (headaches, stomach pain, or muscle/joint pain) to better understand how pain changes over time. It also checks whether certain factors are linked to those pain patterns.
This study explores how migraine headaches, neck pain, and lower back pain may share similar pain mechanisms in the body. Researchers will ask you questions to understand your pain patterns and help identify connections between these conditions.
This study looks at tear samples to find biomarkers that could help diagnose migraine. It involves people with migraine and healthy volunteers.
This trial studies whether stimulating a nerve in the back of the head can reduce chronic cluster-like or related headache attacks. It’s for people whose headaches did not improve after trying several standard prevention treatments.
Hear when a new Migraine trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.