Anakinra for steroid-resistant inner ear inflammation
Treatments studied
Part of Ear, nose & throat clinical trials.
This trial tests an anti-inflammatory drug (anakinra) in people whose inner-ear hearing problems have not improved with steroid treatment. It aims to reduce worsening hearing caused by autoimmune inner ear disease or difficult-to-control Meniere’s disease.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have autoimmune inner ear disease, or Meniere’s disease, that is actively getting worse in one ear
- Your hearing test shows significant loss in the “active” ear, without meaningful improvement after steroids
- You tried steroid treatment (by mouth or into the ear) but either did not improve or could not tolerate steroids, and you have finished steroids
- Imaging does not show certain inner-ear problems (like a nerve tumor or inner-ear shape issues)
- You are not on immune-suppressing medicines like methotrexate or anti-TNF drugs during the study
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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