Aging and brain study for mild memory loss and dementia
Part of Brain & nervous system, Heart & circulation, Mental health clinical trials.
This study checks how age affects memory and thinking, and compares people with mild memory problems, Alzheimer’s disease types, vascular dementia, and healthy controls. You may help researchers understand brain changes using thinking tests, MRI scans, and blood or spinal fluid tests.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be willing to sign informed consent (and keep participating in follow-up visits).
- For the main patient groups, you must have the right diagnosis: mild cognitive impairment, Alzheimer’s disease, familial Alzheimer’s, or vascular dementia.
- If you have MRI eligibility issues (like certain metal in your body or severe claustrophobia), you may not be able to join.
- You must be able to complete thinking/memory tests (MMSE/MoCA and other neuropsychological testing).
- You must be willing to have blood drawn (and possibly spinal fluid tests, depending on study procedures).
- You must not have other brain or body conditions that can also cause memory problems, such as stroke-related brain changes, Parkinson’s disease, major depression, major thyroid/liver/kidney problems, severe anemia, or vitamin B12/folate deficiency.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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