Radiation plus chemotherapy for esophageal cancer that came back
Treatments studied
Part of Cancer, Digestive system clinical trials.
This Phase 3 trial studies giving combined chemotherapy and radiation to treat esophageal cancer that has returned after earlier surgery and/or prior treatments. It may help control the cancer in the area where it comes back, especially when the surgical margins were not fully clear or the cancer is outside the original radiation field.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have esophageal cancer that has come back in the nearby area after surgery
- Your surgery had cancer cells at the cut edge (a positive margin, called R1 or R2)
- The cancer recurrence is outside the area that was previously covered by chemoradiation or radiation, or it returned after chemotherapy
- You have not had any cancer treatment after this recurrence (no new therapy yet)
- You are age 16 to 70, and your performance score (KPS) is above 70
- Your blood counts and liver/kidney health are adequate, and you have no known drug allergy
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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