Needle procedure for Dupuytren’s hand contracture
Part of Bones, joints & muscles, Cancer, Skin clinical trials.
This trial looks at whether a minimally invasive needle procedure can improve hand stiffness caused by Dupuytren’s disease. It may help reduce finger bending that affects how you use your hand.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You’re 18 years or older.
- You have confirmed Dupuytren’s disease (a firm nodule or cord in the palm) causing finger contracture.
- At least one finger has a stiffness/bending problem at the metacarpophalangeal (knuckle) joint of 20° or more.
- You can sign a consent form, and you’re linked with the social security system.
- You are not pregnant or breastfeeding.
- Your condition is not from another hand arthritis/rheumatic disease, and you don’t have hand pain related to inflammation at the start visit.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study tests whether a new injectable enzyme called CNT201 can safely and effectively treat Dupuytren's contracture—a condition where fingers curl and can't straighten. The injection aims to break down the thick tissue cords causing the problem, without surgery.
This trial looks at using radiation after contracture-release surgery for people with Dupuytren’s disease. It may help prevent the hand tightening from coming back and improve hand function.
This study looks at people with Dupuytren's disease (a condition where the fingers bend inward) who are scheduled for a needle procedure to straighten the fingers. Researchers want to track what happens after treatment to better understand the disease.
This trial tests whether surgical “nerve disconnection” (joint denervation) can reduce pain from osteoarthritis in a finger joint. It focuses on people who have ongoing finger pain despite usual treatments for at least 3 months.
This trial tests a minimally invasive procedure that uses a needle to release tight tissue in the hand, and may include a steroid injection. It aims to improve hand finger straightening for people with Dupuytren’s contracture.
This trial tests a less invasive procedure using a needle-knife guided by ultrasound to treat Dupuytren's contracture, which causes fingers to curl. It may be an option if you haven't had prior treatment on the same hand and are in otherwise good health.
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