Needling and possibly steroid shot for Dupuytren’s hand tightness
Part of Bones, joints & muscles, Cancer, Skin clinical trials.
This trial tests a minimally invasive procedure that uses a needle to release tight tissue in the hand, and may include a steroid injection. It aims to improve hand finger straightening for people with Dupuytren’s contracture.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have Dupuytren’s contracture that makes a finger bend at the knuckle (MCP joint) by at least 20°
- The problem is in fingers II through V (index through little finger)
- You can feel a distinct tight cord in your palm/hand
- During the planned treatment, your MCP joint must straighten enough (less than 20° passive extension deficit) to be included
- You must not have had surgery on the affected finger before
- You must be able to communicate and return for follow-up visits
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at people with Dupuytren's disease (a condition where the fingers bend inward) who are scheduled for a needle procedure to straighten the fingers. Researchers want to track what happens after treatment to better understand the disease.
This trial tests a less invasive procedure using a needle-knife guided by ultrasound to treat Dupuytren's contracture, which causes fingers to curl. It may be an option if you haven't had prior treatment on the same hand and are in otherwise good health.
This study tests whether a new injectable enzyme called CNT201 can safely and effectively treat Dupuytren's contracture—a condition where fingers curl and can't straighten. The injection aims to break down the thick tissue cords causing the problem, without surgery.
This study tests if a short course of radiation therapy can help prevent Dupuytren's contracture from coming back after a non-surgical release (like an injection). It may be an option for people whose finger is already bent and cannot touch the table.
This study looks at tiny nerves in Dupuytren disease and whether removing them during surgery helps prevent the disease from coming back. It may help you understand if this surgical approach is right for you.
This study looks at whether a specific hand/cord procedure called aponeurectomy can lower how often Dupuytren’s disease comes back within 2 years. You might be offered surgery and then followed to see how well your symptoms and tightness improve and how often they return.
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