Warfarin safety for people with atrial fibrillation on dialysis
Treatments studied
Part of Brain & nervous system, Heart & circulation, Kidney & urinary, Women’s health & pregnancy clinical trials.
This trial studies whether the blood thinner warfarin is safe and effective for preventing stroke and blood clots in people who have atrial fibrillation and need long-term dialysis. It may help your care team better balance clot prevention against bleeding risk.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be 18 or older and on long-term (chronic) dialysis for kidney failure
- Have atrial fibrillation that is paroxysmal (comes and goes), persistent, or permanent, confirmed on an ECG or a heart monitor
- Be able to understand the study and sign informed consent
- Have a CHA2DS2-VASc score of 2 or higher (not 0 or 1)
- Not need blood thinners for another reason (for example, a recent pulmonary embolism or deep vein clot, or a mechanical heart valve)
- Not have major bleeding risks recently (for example: active bleeding, recent brain bleed, stomach ulcer in the last month, esophageal varices, or an unsafe platelet/liver problem)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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