Clin2
NCT03914768Possibly a fitNot yet recruiting

Personalized immune cell vaccine for brain tumors

Diffuse Intrinsic Pontine Glioma or Glioblastoma

Part of Brain & nervous system, Cancer clinical trials.

This trial tests a personalized vaccine made from your own immune cells (a dendritic cell vaccine) that may help your body fight the brain tumor. It is meant for people with DIPG or glioblastoma who have already tried standard treatments but still have tumors.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
10 people
Ages
1 year to 75 years
Study type
Interventional

Who can take part

  • You must be between 6 months and 80 years old.
  • You must have a type of brain tumor called DIPG or glioblastoma that is still visible on a scan.
  • You must have already received standard treatments like surgery, radiation, and chemotherapy (temozolomide).
  • Your seizures (if any) must be well controlled, and you must be in good enough overall health to function at least 60% on the Karnofsky scale.
  • Your heart, lungs, kidneys, and liver must be working well enough, and you must have adequate blood counts.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06477614Recruiting· Phase 1
Personalized vaccine for advanced solid tumors

This trial tests a personalized vaccine made from your own immune cells (dendritic cells) to help your body fight advanced cancer. It is for people whose cancer has not responded to other treatments.

Guanzhou, Guangdong
NCT06749925Not yet recruiting· Phase 3
Personalized immune cell vaccine for glioblastoma

This trial tests a vaccine made from your own immune cells to fight glioblastoma, a type of brain cancer. It may help your body attack the cancer more effectively after standard treatments.

NCT07678138Not yet recruiting
Personalized dendritic cell vaccine for recurrent glioblastoma

This trial tests an experimental 'vaccine' made from your own immune cells (dendritic cells). The vaccine is designed to train your immune system to attack the brain tumor. It is for people whose glioblastoma has returned or progressed after standard treatment.

NCT02146066AVAILABLE
Personalized vaccine treatment for brain cancer patients who didn't qualify for another study

This trial offers a personalized vaccine (DCVax-L) made from your own tumor cells to patients with glioblastoma (a type of brain cancer) who were not able to join a previous study. The vaccine aims to help your immune system fight the cancer.

Little Rock, Arkansas
NCT05100641Not yet recruiting· Phase 3
Personalized brain cancer vaccine after standard treatment

This trial tests a personalized vaccine made from your own tumor cells, given after standard treatment (surgery and chemo/radiation) for newly diagnosed glioblastoma. The vaccine aims to train your immune system to fight any remaining cancer cells.

NCT07077616Recruiting· Early Phase 1
Personalized vaccine for recurrent glioma

This trial tests a personalized vaccine created by AI to target your specific brain tumor. It is for people with a glioma that came back after standard treatments like surgery, radiation, or chemotherapy, and whose tumor has enough genetic mutations to make the vaccine.

Thessaloniki

Hear when a new Diffuse Intrinsic Pontine Glioma or Glioblastoma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.